Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages
about
From obesity to cancer: a review on proposed mechanisms.Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy.Activated hepatic stellate cells secrete periostin to induce stem cell-like phenotype of residual hepatocellular carcinoma cells after heat treatment.Obesity and Cancer: An Angiogenic and Inflammatory Link.PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity.Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma.Leveraging premalignant biology for immune-based cancer prevention.Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity.Metformin Induces Growth Inhibition and Cell Cycle Arrest by Upregulating MicroRNA34a in Renal Cancer Cells.Type 2 diabetes mellitus is associated with increased risk of pancreatic cancer: A veteran administration registry study.New insight for metformin against bladder cancer.Targeting Tumor-Associated Fibroblasts for Therapeutic Delivery in Desmoplastic Tumors.Metformin in pancreatic cancer treatment: from clinical trials through basic research to biomarker quantification.Cancer and inflammation.Stattic and metformin inhibit brain tumor initiating cells by reducing STAT3-phosphorylation.TGFβ1 overexpression is associated with improved survival and low tumor cell proliferation in patients with early-stage pancreatic ductal adenocarcinoma.Metformin Use Is Associated with Improved Survival in Patients Undergoing Resection for Pancreatic Cancer.Cellular metabolism of tumor-associated macrophages - functional impact and consequences.IL-4 up-regulates cyclooxygenase-1 expression in macrophages.Metformin suppresses cancer initiation and progression in genetic mouse models of pancreatic cancer.Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreatic Ductal Adenocarcinoma.Tendon explant cultures to study the communication between adipose stem cells and native tendon niche.Metabolic coupling and the Reverse Warburg Effect in cancer: Implications for novel biomarker and anticancer agent development.Tumor-associated macrophages, nanomedicine and imaging: the axis of success in the future of cancer immunotherapy.Experimental models of pancreatic cancer desmoplasia.Crucial microRNAs and genes in metformin's anti-pancreatic cancer effect explored by microRNA-mRNA integrated analysis.Feeling Stress: The Mechanics of Cancer Progression and Aggression.Metformin Decreases the Incidence of Pancreatic Ductal Adenocarcinoma Promoted by Diet-induced Obesity in the Conditional KrasG12D Mouse Model.Reengineering the Physical Microenvironment of Tumors to Improve Drug Delivery and Efficacy: From Mathematical Modeling to Bench to Bedside.Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2.IL23 and TGF-ß diminish macrophage associated metastasis in pancreatic carcinoma.Evidence-based complementary treatment of pancreatic cancer: a review of adjunct therapies including paricalcitol, hydroxychloroquine, intravenous vitamin C, statins, metformin, curcumin, and aspirin
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P2860
Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages
description
2015 nî lūn-bûn
@nan
2015 թուականին հրատարակուած գիտական յօդուած
@hyw
2015 թվականին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Metformin Reduces Desmoplasia ...... d Tumor-Associated Macrophages
@ast
Metformin Reduces Desmoplasia ...... d Tumor-Associated Macrophages
@en
Metformin Reduces Desmoplasia ...... d Tumor-Associated Macrophages
@nl
type
label
Metformin Reduces Desmoplasia ...... d Tumor-Associated Macrophages
@ast
Metformin Reduces Desmoplasia ...... d Tumor-Associated Macrophages
@en
Metformin Reduces Desmoplasia ...... d Tumor-Associated Macrophages
@nl
prefLabel
Metformin Reduces Desmoplasia ...... d Tumor-Associated Macrophages
@ast
Metformin Reduces Desmoplasia ...... d Tumor-Associated Macrophages
@en
Metformin Reduces Desmoplasia ...... d Tumor-Associated Macrophages
@nl
P2093
P2860
P1433
P1476
Metformin Reduces Desmoplasia ...... d Tumor-Associated Macrophages
@en
P2093
Dai Fukumura
Joao Incio
Priya Suboj
Rakesh K Jain
Shan M Chin
Suboj Babykutty
Trupti Vardam-Kaur
P2860
P304
P356
10.1371/JOURNAL.PONE.0141392
P407
P577
2015-01-01T00:00:00Z