A Single Amino Acid Substitution in the West Nile Virus Nonstructural Protein NS2A Disables Its Ability To Inhibit Alpha/Beta Interferon Induction and Attenuates Virus Virulence in Mice - Wikidata - wikimedia - TriplyDB

A Single Amino Acid Substitution in the West Nile Virus Nonstructural Protein NS2A Disables Its Ability To Inhibit Alpha/Beta Interferon Induction and Attenuates Virus Virulence in Mice

A Single Amino Acid Substitution in the West Nile Virus Nonstructural Protein NS2A Disables Its Ability To Inhibit Alpha/Beta Interferon Induction and Attenuates Virus Virulence in Mice

http://www.wikidata.org/entity/Q27473041

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Rotavirus NSP1 inhibits NFkappaB activation by inducing proteasome-dependent degradation of beta-TrCP: a novel mechanism of IFN antagonism The role of viral persistence in flavivirus biology Comparative genomic analysis of pre-epidemic and epidemic Zika virus strains for virological factors potentially associated with the rapidly expanding epidemic West Nile Virus Temperature Sensitivity and Avian Virulence Are Modulated by NS1-2B Polymorphisms Limited Effects of Type I Interferons on Kyasanur Forest Disease Virus in Cell Culture West Nile Virus: biology, transmission, and human infection Vaccines in development against West Nile virus Understanding the dengue viruses and progress towards their control Mechanism of West Nile virus neuroinvasion: a critical appraisal RNA structures required for production of subgenomic flavivirus RNA A Novel Synthetic TLR-4 Agonist Adjuvant Increases the Protective Response to a Clinical-Stage West Nile Virus Vaccine Antigen in Multiple Formulations TRIM52 inhibits Japanese Encephalitis Virus replication by degrading the viral NS2A PKR and RNase L Contribute to Protection against Lethal West Nile Virus Infection by Controlling Early Viral Spread in the Periphery and Replication in Neurons Pathogenesis of West Nile Virus Infection: a Balance between Virulence, Innate and Adaptive Immunity, and Viral Evasion Translation of the Flavivirus Kunjin NS3 Gene in cis but Not Its RNA Sequence or Secondary Structure Is Essential for Efficient RNA Packaging A Combination of Naturally Occurring Mutations in North American West Nile Virus Nonstructural Protein Genes and in the 3' Untranslated Region Alters Virus Phenotype Cell-Specific IRF-3 Responses Protect against West Nile Virus Infection by Interferon-Dependent and -Independent Mechanisms Early Production of Type I Interferon during West Nile Virus Infection: Role for Lymphoid Tissues in IRF3-Independent Interferon Production A mouse cell-adapted NS4B mutation attenuates West Nile virus RNA synthesis West Nile Virus-Induced Neuroinflammation: Glial Infection and Capsid Protein-Mediated Neurovirulence Differential Expression of Interferon (IFN) Regulatory Factors and IFN-Stimulated Genes at Early Times after West Nile Virus Infection of Mouse Embryo Fibroblasts Characterization of a small plaque variant of West Nile virus isolated in New York in 2000 Establishment and Maintenance of the Innate Antiviral Response to West Nile Virus Involves both RIG-I and MDA5 Signaling through IPS-1 Role of Nonstructural Protein NS2A in Flavivirus Assembly West Nile Virus Nonstructural Protein 1 Inhibits TLR3 Signal Transduction Virus and Host Determinants of West Nile Virus Pathogenesis Innate immune evasion by hepatitis C virus and West Nile virus Progress on the development of therapeutics against West Nile virus NS1' of Flaviviruses in the Japanese Encephalitis Virus Serogroup Is a Product of Ribosomal Frameshifting and Plays a Role in Viral Neuroinvasiveness Flavitrack analysis of the structure and function of West Nile non-structural proteins Membrane Topology and Function of Dengue Virus NS2A Protein Inhibition of type I interferon induction and signalling by mosquito-borne flaviviruses West nile virus: characteristics of an african virus adapting to the third millennium world.Epidemiological and clinical aspects on West Nile virus, a globally emerging pathogen.The role of interferon antagonist, non-structural proteins in the pathogenesis and emergence of arboviruses.A critical determinant of neurological disease associated with highly pathogenic tick-borne flavivirus in mice Abrogation of TLR3 inhibition by discrete amino acid changes in the C-terminal half of the West Nile virus NS1 protein.West Nile virus and its emergence in the United States of America.Chikungunya virus arthritis in adult wild-type mice.Tick-borne encephalitis virus delays interferon induction and hides its double-stranded RNA in intracellular membrane vesicles.

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A Single Amino Acid Substitution in the West Nile Virus Nonstructural Protein NS2A Disables Its Ability To Inhibit Alpha/Beta Interferon Induction and Attenuates Virus Virulence in Mice

http://www.wikidata.org/entity/Q27473041

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2006 nî lūn-bûn

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2006 թուականի Մարտին հրատարակուած գիտական յօդուած

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2006 թվականի մարտին հրատարակված գիտական հոդված

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2006年の論文

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A Single Amino Acid Substituti ...... nuates Virus Virulence in Mice

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A Single Amino Acid Substituti ...... nuates Virus Virulence in Mice

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A Single Amino Acid Substituti ...... nuates Virus Virulence in Mice

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A Single Amino Acid Substituti ...... nuates Virus Virulence in Mice

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JVI.80.5.2396-2404.2006

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Journal of Virology

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A Single Amino Acid Substituti ...... nuates Virus Virulence in Mice

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David C Clark

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Mario Lobigs

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Roy A Hall

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Wen Jun Liu

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Xiang Ju Wang

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P2860

Dengue virus inhibits alpha interferon signaling by reducing STAT2 expression

Blocking of the alpha interferon-induced Jak-Stat signaling pathway by Japanese encephalitis virus infection

Inhibition of interferon signaling by dengue virus

Differential virulence of West Nile strains for American crows.

Flavivirus Activates Phosphatidylinositol 3-Kinase Signaling To Block Caspase-Dependent Apoptotic Cell Death at the Early Stage of Virus Infection

Activation of the N-Ras-PI3K-Akt-mTOR pathway by hepatitis C virus: control of cell survival and viral replication.

Inhibition of Transcription and Translation in Sindbis Virus-Infected Cells

Infectious cDNA clone of the epidemic west nile virus from New York City

Molecular and Functional Analyses of Kunjin Virus Infectious cDNA Clones Demonstrate the Essential Roles for NS2A in Virus Assembly and for a Nonconservative Residue in NS3 in RNA Replication

Subgenomic replicons of the flavivirus Kunjin: construction and applications

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2396-404

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scholarly article

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3347508

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10.1128/JVI.80.5.2396-2404.2006

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5

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80

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Alexander A. Khromykh

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2006-03-01T00:00:00Z

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7302835

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16474146

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West Nile virus

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1395377

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