Monoclonal Antibodies That Bind to Common Epitopes on the Dengue Virus Type 2 Nonstructural-1 and Envelope Glycoproteins Display Weak Neutralizing Activity and Differentiated Responses to Virulent Strains: Implications for Pathogenesis and Vaccines

Monoclonal Antibodies That Bind to Common Epitopes on the Dengue Virus Type 2 Nonstructural-1 and Envelope Glycoproteins Display Weak Neutralizing Activity and Differentiated Responses to Virulent Strains: Implications for Pathogenesis and Vaccines

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http://www.wikidata.org/entity/Q27485490

Q27485490

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Possible future monoclonal antibody (mAb)-based therapy against arbovirus infections Antibodies Induced by Dengue Virus Type 1 and 2 Envelope Domain III Recombinant Proteins in Monkeys Neutralize Strains with Different Genotypes Flavivirus NS1 Structures Reveal Surfaces for Associations with Membranes and the Immune System Dengue Virus Non-structural Protein 1 Modulates Infectious Particle Production via Interaction with the Structural Proteins A highly conserved region between amino acids 221 and 266 of dengue virus non-structural protein 1 is a major epitope region in infected patients The NS1 glycoprotein can generate dramatic antibody-enhanced dengue viral replication in normal out-bred mice resulting in lethal multi-organ disease.Epitope reactions can be gauged by relative antibody discriminating specificity (RADS) values supported by deletion, substitution and cysteine bridge formation analyses: potential uses in pathogenesis studies.Evolution of dengue virus type 3 genotype III in Venezuela: diversification, rates and population dynamics.Mapping the interactions of dengue virus NS1 protein with human liver proteins using a yeast two-hybrid system: identification of C1q as an interacting partner.B-cell responses during primary and secondary dengue virus infections in humans.Computational Identification of Antibody Epitopes on the Dengue Virus NS1 Protein.A simple, inexpensive, robust and sensitive dot-blot assay for equal detection of the nonstructural-1 glycoprotein of all dengue virus serotypes.Antibody recognition of the dengue virus proteome and implications for development of vaccines.Dengue Virus NS1 Protein as a Diagnostic Marker: Commercially Available ELISA and Comparison to qRT-PCR and Serological Diagnostic Assays Currently Used by the State of Florida.Computational prediction of immunodominant antigenic regions & potential protective epitopes for dengue vaccination.[West Nile virus. II. Immunopathophysiology in humans].

P2860

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P2860

Monoclonal Antibodies That Bind to Common Epitopes on the Dengue Virus Type 2 Nonstructural-1 and Envelope Glycoproteins Display Weak Neutralizing Activity and Differentiated Responses to Virulent Strains: Implications for Pathogenesis and Vaccines

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http://www.wikidata.org/entity/Q27485490

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2008 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի մարտին հրատարակված գիտական հոդված

@hy

article scientifique (publié 2008-03)

@fr

articolo scientifico (pubblicato il 2008-03)

@it

artigo científico (publicado na 2008-03)

@pt

artículu científicu espublizáu en 2008

@ast

im März 2008 veröffentlichter wissenschaftlicher Artikel

@de

scientific article (publication date: March 2008)

@en

vedecký článok (publikovaný 2008-03)

@sk

vetenskaplig artikel (publicerad på 2008-03)

@sv