Attenuating mutations in glycoproteins E1 and E2 of Sindbis virus produce a highly attenuated strain when combined in vitro
about
Alpha/beta interferon protects adult mice from fatal Sindbis virus infection and is an important determinant of cell and tissue tropismEffect of E2 envelope glycoprotein cytoplasmic domain mutations on Sindbis virus pathogenesisDeduced consensus sequence of Sindbis virus strain AR339: mutations contained in laboratory strains which affect cell culture and in vivo phenotypesA putative receptor for Venezuelan equine encephalitis virus from mosquito cellsTransient translocation of the cytoplasmic (endo) domain of a type I membrane glycoprotein into cellular membranesStructural and Nonstructural Protein Genome Regions of Eastern Equine Encephalitis Virus Are Determinants of Interferon Sensitivity and Murine VirulenceLethality of PE2 incorporation into Sindbis virus can be suppressed by second-site mutations in E3 and E2The amino-terminal residue of Sindbis virus glycoprotein E2 influences virus maturation, specific infectivity for BHK cells, and virulence in miceMolecular analysis of neurovirulent strains of Sindbis virus that evolve during persistent infection of scid miceConformational alteration of Sindbis virion glycoproteins induced by heat, reducing agents, or low pHMutational analysis of a virulence locus in the E2 glycoprotein gene of Sindbis virusThe alphaviruses: gene expression, replication, and evolutionCapped RNA transcripts of full-length cDNA clones of swine hepatitis E virus are replication competent when transfected into Huh7 cells and infectious when intrahepatically inoculated into pigs.Mapping of genetic determinants of rubella virus associated with growth in joint tissue.Replicase complex genes of Semliki Forest virus confer lethal neurovirulenceInfection of neonatal mice with sindbis virus results in a systemic inflammatory response syndrome.Three amino acid mutations (F51L, T59A, and S390L) in the capsid protein of the hepatitis E virus collectively contribute to virus attenuation.A single amino acid change in the E2 glycoprotein of Sindbis virus confers neurovirulence by altering an early step of virus replication.Viral determinants of age-dependent virulence of Sindbis virus for miceTwo amino acid mutations in the capsid protein of type 2 porcine circovirus (PCV2) enhanced PCV2 replication in vitro and attenuated the virus in vivo.Mutations in rotavirus nonstructural glycoprotein NSP4 are associated with altered virus virulence.A single nucleotide change in the 5' noncoding region of Sindbis virus confers neurovirulence in rats.
P2860
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P2860
Attenuating mutations in glycoproteins E1 and E2 of Sindbis virus produce a highly attenuated strain when combined in vitro
description
1990 nî lūn-bûn
@nan
1990 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Attenuating mutations in glyco ...... strain when combined in vitro
@ast
Attenuating mutations in glyco ...... strain when combined in vitro
@en
Attenuating mutations in glyco ...... strain when combined in vitro
@nl
type
label
Attenuating mutations in glyco ...... strain when combined in vitro
@ast
Attenuating mutations in glyco ...... strain when combined in vitro
@en
Attenuating mutations in glyco ...... strain when combined in vitro
@nl
prefLabel
Attenuating mutations in glyco ...... strain when combined in vitro
@ast
Attenuating mutations in glyco ...... strain when combined in vitro
@en
Attenuating mutations in glyco ...... strain when combined in vitro
@nl
P2860
P1433
P1476
Attenuating mutations in glyco ...... strain when combined in vitro
@en
P2093
R E Johnston
P2860
P304
P577
1990-09-01T00:00:00Z