Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus Replication - Wikidata - wikimedia - TriplyDB

Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus Replication

Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus Replication

http://www.wikidata.org/entity/Q27489697

about

The lipid kinase phosphatidylinositol-4 kinase III alpha regulates the phosphorylation status of hepatitis C virus NS5A Annexin A2 is involved in the formation of hepatitis C virus replication complex on the lipid raft Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment Hepatitis C virus NS5A protein interacts with phosphatidylinositol 4-kinase type IIIalpha and regulates viral propagation Systems virology identifies a mitochondrial fatty acid oxidation enzyme, dodecenoyl coenzyme A delta isomerase, required for hepatitis C virus replication and likely pathogenesis Mechanisms of Cellular Membrane Reorganization to Support Hepatitis C Virus Replication Host-Targeting Agents to Prevent and Cure Hepatitis C Virus Infection Curing a viral infection by targeting the host: the example of cyclophilin inhibitors Autophagy in hepatitis C virus-host interactions: potential roles and therapeutic targets for liver-associated diseases Phosphoinositides: tiny lipids with giant impact on cell regulation Molecular determinants and dynamics of hepatitis C virus secretion Increased susceptibility of Huh7 cells to HCV replication does not require mutations in RIG-I Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approaches A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay Plasticity of PI4KIIIα interactions at the plasma membrane PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity Phosphatidylinositol 4-kinases: hostages harnessed to build panviral replication platforms Viral reorganization of the secretory pathway generates distinct organelles for RNA replication.Cinderella story: PI4P goes from precursor to key signaling molecule Metabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity Hepatitis C virus replication and Golgi function in brefeldin a-resistant hepatoma-derived cells Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M.Replication vesicles are load- and choke-points in the hepatitis C virus lifecycle.A major determinant of cyclophilin dependence and cyclosporine susceptibility of hepatitis C virus identified by a genetic approach Rab18 facilitates dengue virus infection by targeting fatty acid synthase to sites of viral replication Involvement of hepatitis C virus NS5A hyperphosphorylation mediated by casein kinase I-α in infectious virus production.Glycogen synthase kinase 3β inhibitors prevent hepatitis C virus release/assembly through perturbation of lipid metabolism Integrative functional genomics of hepatitis C virus infection identifies host dependencies in complete viral replication cycle c-Fos regulates hepatitis C virus propagation.Dengue virus-induced autophagy regulates lipid metabolism West Nile virus replication requires fatty acid synthesis but is independent on phosphatidylinositol-4-phosphate lipids The role of the phosphatidylinositol 4-kinase PI4KA in hepatitis C virus-induced host membrane rearrangement.Normalizing for individual cell population context in the analysis of high-content cellular screens.ARF1 and GBF1 generate a PI4P-enriched environment supportive of hepatitis C virus replication.Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis.The dependence of viral RNA replication on co-opted host factors.Barriers of hepatitis C virus interspecies transmission Self-enhancement of hepatitis C virus replication by promotion of specific sphingolipid biosynthesis.Phosphatidylinositol 4-kinase III beta is a target of enviroxime-like compounds for antipoliovirus activity.

P2860

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P2860

Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus Replication

http://www.wikidata.org/entity/Q27489697

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Class III Phosphatidylinositol ...... Hepatitis C Virus Replication

@ast

Class III Phosphatidylinositol ...... Hepatitis C Virus Replication

@en

Class III Phosphatidylinositol ...... Hepatitis C Virus Replication

@nl

type

label

Class III Phosphatidylinositol ...... Hepatitis C Virus Replication

@ast

Class III Phosphatidylinositol ...... Hepatitis C Virus Replication

@en

Class III Phosphatidylinositol ...... Hepatitis C Virus Replication

@nl

prefLabel

Class III Phosphatidylinositol ...... Hepatitis C Virus Replication

@ast

Class III Phosphatidylinositol ...... Hepatitis C Virus Replication

@en

Class III Phosphatidylinositol ...... Hepatitis C Virus Replication

@nl

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Journal of Virology

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Class III Phosphatidylinositol ...... Hepatitis C Virus Replication

@en

P2093

Brigitte Wiedmann

http://www.w3.org/2001/XMLSchema#string

Christopher J Wilson

http://www.w3.org/2001/XMLSchema#string

Craig Mickanin

http://www.w3.org/2001/XMLSchema#string

Gerard Joberty

http://www.w3.org/2001/XMLSchema#string

Ivan Cornellataracido

http://www.w3.org/2001/XMLSchema#string

Jason Borawski

http://www.w3.org/2001/XMLSchema#string

Jeremy Baryza

http://www.w3.org/2001/XMLSchema#string

Joanna E Mathy

http://www.w3.org/2001/XMLSchema#string

John Tallarico

http://www.w3.org/2001/XMLSchema#string

Juliet Leighton-Davies

http://www.w3.org/2001/XMLSchema#string

P2860

Whole genome functional analysis identifies novel components required for mitotic spindle integrity in human cells.

Binding of hepatitis C virus to CD81

Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein

Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication

Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase

Cellular cofactors affecting hepatitis C virus infection and replication

Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus

Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells

Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations.

Robust hepatitis C virus infection in vitro.

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10058-74

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scholarly article

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1466260

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P356

10.1128/JVI.02418-08

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P433

19

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P478

83

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P577

2009-10-01T00:00:00Z

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19605471

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2748049

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