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The Role of Medical Structural Genomics in Discovering New Drugs for Infectious Diseases

The Role of Medical Structural Genomics in Discovering New Drugs for Infectious Diseases

http://www.wikidata.org/entity/Q27489856

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Structure of a Burkholderia pseudomallei trimeric autotransporter adhesin head Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase.Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei SAD phasing using iodide ions in a high-throughput structural genomics environment Crystal Structure of Toxoplasma gondii Porphobilinogen Synthase Structure of the prolyl-tRNA synthetase from the eukaryotic pathogenGiardia lamblia The Protein Maker: an automated system for high-throughput parallel purification Structures of a putative ζ-class glutathione S -transferase from the pathogenic fungus Coccidioides immitis Solution-state NMR structure and biophysical characterization of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis The key role of genomics in modern vaccine and drug design for emerging infectious diseases Genomics of emerging infectious disease: A PLoS collection Unmet challenges of structural genomics Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms Fragment screening of infectious disease targets in a structural genomics environment Microbial genomics and infectious diseases.Structural genomics of infectious disease drug targets: the SSGCID.Low potency toxins reveal dense interaction networks in metabolism.Solid-state NMR spectroscopy on complex biomolecules.Structural and Functional Highlights of Vacuolar Soluble Protein 1 from Pathogen Trypanosoma brucei brucei.Toward prediction of functional protein pockets using blind docking and pocket search algorithms.

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The Role of Medical Structural Genomics in Discovering New Drugs for Infectious Diseases

http://www.wikidata.org/entity/Q27489856

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2009 nî lūn-bûn

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2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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The Role of Medical Structural Genomics in Discovering New Drugs for Infectious Diseases

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The Role of Medical Structural Genomics in Discovering New Drugs for Infectious Diseases

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The Role of Medical Structural Genomics in Discovering New Drugs for Infectious Diseases

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The Role of Medical Structural Genomics in Discovering New Drugs for Infectious Diseases

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The Role of Medical Structural Genomics in Discovering New Drugs for Infectious Diseases

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The Role of Medical Structural Genomics in Discovering New Drugs for Infectious Diseases

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The Role of Medical Structural Genomics in Discovering New Drugs for Infectious Diseases

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JOURNAL.PCBI.1000530

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PLOS Computational Biology

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The Role of Medical Structural Genomics in Discovering New Drugs for Infectious Diseases

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Lance J Stewart

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P2860

Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin

Shape shifting leads to small-molecule allosteric drug discovery

The worldwide Protein Data Bank (wwPDB): ensuring a single, uniform archive of PDB data

Design, expression, and purification of a Flaviviridae polymerase using a high-throughput approach to facilitate crystal structure determination

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Characterization and crystal structure of a high-affinity pentavalent receptor-binding inhibitor for cholera toxin and E. coli heat-labile enterotoxin

A complete structural description of the catalytic cycle of yeast pyrophosphatase

Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography †

Recent developments in fragment-based drug discovery

Structural genomics of pathogenic protozoa: an overview

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Wesley C Van Voorhis

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2009-10-01T00:00:00Z

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infectious disease

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