Impaired antiviral activity of interferon alpha against hepatitis C virus 2a in Huh-7 cells with a defective Jak-Stat pathway
about
SH2 modified STAT1 induces HLA-I expression and improves IFN-γ signaling in IFN-α resistant HCV replicon cells.Intracytoplasmic stable expression of IgG1 antibody targeting NS3 helicase inhibits replication of highly efficient hepatitis C Virus 2a clone.Hepatitis C virus infection impairs IRF-7 translocation and Alpha interferon synthesis in immortalized human hepatocytesIntracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replication.Impaired expression of type I and type II interferon receptors in HCV-associated chronic liver disease and liver cirrhosis.Hepatocellular carcinoma xenograft supports HCV replication: a mouse model for evaluating antivirals.IFN-λ Inhibits MiR-122 Transcription through a Stat3-HNF4α Inflammatory Feedback Loop in an IFN-α Resistant HCV Cell Culture System.Highly pathogenic avian influenza virus infection in chickens but not ducks is associated with elevated host immune and pro-inflammatory responses.Interferon and ribavirin combination treatment synergistically inhibit HCV internal ribosome entry site mediated translation at the level of polyribosome formation.Development and optimization of nanosomal formulations for siRNA delivery to the liverInhibition of hepatitis C virus replication by intracellular delivery of multiple siRNAs by nanosomes.Epigenetic regulation of MicroRNA-122 by peroxisome proliferator activated receptor-gamma and hepatitis b virus X protein in hepatocellular carcinoma cells.Evasion of superinfection exclusion and elimination of primary viral RNA by an adapted strain of hepatitis C virus.HCV infection selectively impairs type I but not type III IFN signaling.Hepatitis C virus-host interactions: Etiopathogenesis and therapeutic strategies.Gene expression profiles of T cells from hepatitis E virus infected patients in acute and resolving phase.Free fatty acids induce ER stress and block antiviral activity of interferon alpha against hepatitis C virus in cell culture.Stability of lyophilized siRNA nanosome formulations.Mechanism of HCV's resistance to IFN-α in cell culture involves expression of functional IFN-α receptor 1.Anti-hepatitis C virus activity of 3-hydroxy caruilignan C from Swietenia macrophylla stems.
P2860
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P2860
Impaired antiviral activity of interferon alpha against hepatitis C virus 2a in Huh-7 cells with a defective Jak-Stat pathway
description
2010 nî lūn-bûn
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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
Impaired antiviral activity of ...... h a defective Jak-Stat pathway
@ast
Impaired antiviral activity of ...... h a defective Jak-Stat pathway
@en
Impaired antiviral activity of ...... h a defective Jak-Stat pathway
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type
label
Impaired antiviral activity of ...... h a defective Jak-Stat pathway
@ast
Impaired antiviral activity of ...... h a defective Jak-Stat pathway
@en
Impaired antiviral activity of ...... h a defective Jak-Stat pathway
@nl
prefLabel
Impaired antiviral activity of ...... h a defective Jak-Stat pathway
@ast
Impaired antiviral activity of ...... h a defective Jak-Stat pathway
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Impaired antiviral activity of ...... h a defective Jak-Stat pathway
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P2093
P2860
P356
P1433
P1476
Impaired antiviral activity of ...... h a defective Jak-Stat pathway
@en
P2093
Gus Kousoulas
Partha K Chandra
Sibnarayan Datta
Sidhartha Hazari
Srikanta Dash
Timothy P Foster
P2860
P2888
P356
10.1186/1743-422X-7-36
P577
2010-02-11T00:00:00Z
P6179
1004771206