Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding
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Dicyema Pax6 and Zic: tool-kit genes in a highly simplified bilaterianMutations in MITF and PAX3 cause "splashed white" and other white spotting phenotypes in horsesPapillorenal syndrome-causing missense mutations in PAX2/Pax2 result in hypomorphic alleles in mouse and humanGenetic architecture of complex traits and accuracy of genomic prediction: coat colour, milk-fat percentage, and type in Holstein cattle as contrasting model traitsModulation of PAX6 homeodomain function by the paired domainThe MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoterIntertwined structure of the DNA-binding domain of intron endonuclease I-TevI with its substrate.Structure of the N-terminal fragment of topoisomerase V reveals a new family of topoisomerases.Id helix-loop-helix proteins antagonize pax transcription factor activity by inhibiting DNA bindingStructure of the Escherichia coli leucine-responsive regulatory protein Lrp reveals a novel octameric assemblyThe third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactionsPAX6 mutations: genotype-phenotype correlationsHomeodomain proteins: an updateStructural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptorsCrystal structure of the CENP-B protein-DNA complex: the DNA-binding domains of CENP-B induce kinks in the CENP-B box DNA.Structural basis for LEAFY floral switch function and similarity with helix-turn-helix proteinsThe Solution Structure of DNA-free Pax-8 Paired Box Domain Accounts for Redox Regulation of Transcriptional Activity in the Pax Protein FamilyRecognition of AT-Rich DNA Binding Sites by the MogR RepressorMolecular Architecture of the Mos1 Paired-End Complex: The Structural Basis of DNA Transposition in a EukaryoteAutoregulation and maturity onset diabetes of the young transcription factors control the human PAX4 promoterFunctional analysis of a mutation in PAX9 associated with familial tooth agenesis in humansA missense mutation in PAX9 in a family with distinct phenotype of oligodontiaFunctional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferationCancer missense mutations alter binding properties of proteins and their interaction networksNeurosensory Differentiation and Innervation Patterning in the Human Fetal Vestibular End Organs between the Gestational Weeks 8-12.Disruption of autoregulatory feedback by a mutation in a remote, ultraconserved PAX6 enhancer causes aniridia.A novel mutation of PAX6 in Chinese patients with new clinical features of Peters' anomalyDNA familial binding profiles made easy: comparison of various motif alignment and clustering strategies.Eyg and Ey Pax proteins act by distinct transcriptional mechanisms in Drosophila development.Daughterless homodimer synergizes with Eyeless to induce Atonal expression and retinal neuron differentiationHighly conserved amino acids in Pax and Ets proteins are required for DNA binding and ternary complex assembly.Identification of a novel pax8 gene sequence variant in four members of the same family: from congenital hypothyroidism with thyroid hypoplasia to mild subclinical hypothyroidism.Two DNA-binding domains of Mga are required for virulence gene activation in the group A streptococcus.Functional redundancy of two Pax-like proteins in transcriptional activation of cyst wall protein genes in Giardia lamblia.A novel pax-like protein involved in transcriptional activation of cyst wall protein genes in Giardia lamblia.Crystallization and preliminary X-ray diffraction analysis of the Pax9 paired domain bound to a DC5 enhancer DNA element.Using protein design algorithms to understand the molecular basis of disease caused by protein-DNA interactions: the Pax6 example.Missense mutations of human homeoboxes: A review.Identification of in vivo DNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development.Inhibition of Pax2 Transcription Activation with a Small Molecule that Targets the DNA Binding Domain.
P2860
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P2860
Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Crystal structure of the human ...... minal subdomain in DNA binding
@ast
Crystal structure of the human ...... minal subdomain in DNA binding
@en
Crystal structure of the human ...... minal subdomain in DNA binding
@nl
type
label
Crystal structure of the human ...... minal subdomain in DNA binding
@ast
Crystal structure of the human ...... minal subdomain in DNA binding
@en
Crystal structure of the human ...... minal subdomain in DNA binding
@nl
prefLabel
Crystal structure of the human ...... minal subdomain in DNA binding
@ast
Crystal structure of the human ...... minal subdomain in DNA binding
@en
Crystal structure of the human ...... minal subdomain in DNA binding
@nl
P2093
P2860
P3181
P356
P1433
P1476
Crystal structure of the human ...... minal subdomain in DNA binding
@en
P2093
P2860
P304
P3181
P356
10.1101/GAD.13.10.1263
P50
P577
1999-05-15T00:00:00Z