Crystal structure of human quinone reductase type 2, a metalloflavoprotein
about
Sequence-structure analysis of FAD-containing proteinsUpdate of the NAD(P)H:quinone oxidoreductase (NQO) gene familyKinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2Expansion of substrate specificity and catalytic mechanism of azoreductase by X-ray crystallography and site-directed mutagenesisThe structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2)Synthesis of Casimiroin and Optimization of Its Quinone Reductase 2 and Aromatase Inhibitory ActivitiesKTN (RCK) Domains Regulate K+ Channels and Transporters by Controlling the Dimer-Hinge ConformationMechanism-Based Inhibition of Quinone Reductase 2 (NQO2): Selectivity for NQO2 over NQO1 and Structural Basis for Flavoprotein InhibitionIn Silico Screening Reveals Structurally Diverse, Nanomolar Inhibitors of NQO2 That Are Functionally Active in Cells and Can Modulate NF- B SignalingStructures of the PutA peripheral membrane flavoenzyme reveal a dynamic substrate-channeling tunnel and the quinone-binding siteStructural and biochemical characterization of MdaB from cariogenic Streptococcus mutans reveals an NADPH-specific quinone oxidoreductaseLot6p from Saccharomyces cerevisiae is a FMN-dependent reductase with a potential role in quinone detoxification.Crystal structure of quinone reductase 2 in complex with resveratrolFunctional Annotation of a Presumed Nitronate Monoxygenase Reveals a New Class of NADH:Quinone ReductasesIdentification of an ancillary protein, YabF, required for activity of the KefC glutathione-gated potassium efflux system in Escherichia coliChloroquine binding reveals flavin redox switch function of quinone reductase 2.NRH:quinone oxidoreductase 2-deficient mice are highly susceptible to radiation-induced B-cell lymphomasCircadian rhythms, oxidative stress, and antioxidative defense mechanisms.Quinone reductases multitasking in the metabolic world.Therapeutic potential of melatonin ligands.Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide.Quinone reductase 2 is a catechol quinone reductaseEvidence for NQO2-mediated reduction of the carcinogenic estrogen ortho-quinonesKefF, the regulatory subunit of the potassium efflux system KefC, shows quinone oxidoreductase activity.Crystallization and preliminary X-ray characterization of the Bacillus amyloliquefaciens YwrO enzyme.A fascination with enzymes: the journey not the arrival matters.The two common polymorphic forms of human NRH-quinone oxidoreductase 2 (NQO2) have different biochemical properties.Functions of NQO1 in Cellular Protection and CoQ10 Metabolism and its Potential Role as a Redox Sensitive Molecular Switch.A tandem orthogonal proteolysis strategy for high-content chemical proteomics.Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases.Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity.Evidence for NQO1 and NQO2 catalyzed reduction of ortho- and para-quinone methides.Flavin-dependent thymidylate synthase: N5 of flavin as a Methylene carrier.Inhibitors or toxins? Large library target-specific screening of fullerene-based nanoparticles for drug design purpose.Three-dimensional structure of AzoR from Escherichia coli. An oxidereductase conserved in microorganisms.How Diverse Are the Protein-Bound Conformations of Small-Molecule Drugs and Cofactors?
P2860
Q24644689-6032EAB7-7C42-4EA7-9A49-1973E41BD76EQ27497568-CA5D5C8B-6DFF-4798-B52E-2B4DB2D30FCDQ27649797-87217C2B-63D7-4293-949D-ED9CDA2D64DEQ27650066-07007608-6E9C-4642-819E-DCCDC4948A4FQ27653890-8607D164-2412-4398-AA3F-813247137DE3Q27654021-37819BDB-C889-4658-B260-D2F6F865C5DDQ27655925-C0AFCD5C-15E1-4C3D-B14B-F398FD97F27AQ27667472-69D97A24-BE56-4A47-9FFA-B95E901BB6DCQ27675614-A747921B-E231-4F43-BFEF-35B9F0F51820Q27681821-3604EC34-0DA6-4923-AC16-120E6E2A0C5BQ27689717-57E8C61B-1CFC-4645-96C4-06F88B8F8856Q27935414-0C5770ED-0BD6-4C98-AA23-2BAF6C38AF09Q28280502-DDC4079C-9B05-43E3-A226-7DF38FAA4C66Q28492608-1EA632DA-3F16-41BB-B70A-F4A1C9A63A9BQ33923201-68D14BFB-D1BC-4033-8074-6DC50182C35AQ34331796-4487ED61-C1AE-405E-8B4D-4D752781C823Q35055410-E0283D33-90CD-4FC6-99FD-720BFC38C67DQ35609478-01D84EB6-3826-4CA7-81C1-99E7637A0ADCQ35956182-A44AE6AD-194F-478A-BB08-C74687FF9AD1Q36474524-66696620-96FC-4F51-8586-A6F9800991D1Q36476624-319FCA5C-C640-4734-8F81-55FC6C7A89B9Q36856168-E2C91FEA-2304-4140-86A1-3EC9571B5470Q37352680-DAA14625-C9D6-4BC3-AA5A-C5DB78CA608AQ38285475-AC6EF924-3E55-41A4-8740-35F422A951ABQ38293181-3183C0E5-81D0-43B3-9C24-ACAEC867B4D3Q38575125-34FA1E4E-D7C0-498A-AC9C-03EB91C4F9ADQ40296515-5A429744-D253-41D3-A42F-96819FD218DBQ41539407-1E18AE79-3345-4B52-8629-09BF8FE21A60Q42547311-523938C2-F666-4A89-8EA8-9687B7E8D988Q42762319-855C5D94-C620-408B-B3D7-2468B854EC58Q44156025-CC1AD692-C41B-4344-A3FB-97BE2CF7B413Q46402017-2469CEDD-5971-435C-A47E-812FD7BAB867Q47933924-6413FC3E-4306-448D-8FB9-B9704BF08D9DQ48145360-C31C55F1-A575-431D-AF4B-3F8BCE28AFDCQ53623694-B71F97AE-A2BE-45ED-881C-6639BE5154F9Q54327473-C91C9978-0A48-4887-9DF4-569D050B3D7A
P2860
Crystal structure of human quinone reductase type 2, a metalloflavoprotein
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Crystal structure of human quinone reductase type 2, a metalloflavoprotein
@ast
Crystal structure of human quinone reductase type 2, a metalloflavoprotein
@en
Crystal structure of human quinone reductase type 2, a metalloflavoprotein
@nl
type
label
Crystal structure of human quinone reductase type 2, a metalloflavoprotein
@ast
Crystal structure of human quinone reductase type 2, a metalloflavoprotein
@en
Crystal structure of human quinone reductase type 2, a metalloflavoprotein
@nl
prefLabel
Crystal structure of human quinone reductase type 2, a metalloflavoprotein
@ast
Crystal structure of human quinone reductase type 2, a metalloflavoprotein
@en
Crystal structure of human quinone reductase type 2, a metalloflavoprotein
@nl
P2093
P356
P1433
P1476
Crystal structure of human quinone reductase type 2, a metalloflavoprotein
@en
P2093
P304
P356
10.1021/BI990799V
P407
P577
1999-08-01T00:00:00Z