about
Structural diversity of streptokinase and activation of human plasminogenCoevolutionary patterns in plasminogen activationPathogen activators of plasminogenPlasminogen substrate recognition by the streptokinase-plasminogen catalytic complex is facilitated by Arg253, Lys256, and Lys257 in the streptokinase beta-domain and kringle 5 of the substrate.Involvement of a nine-residue loop of streptokinase in the generation of macromolecular substrate specificity by the activator complex through interaction with substrate kringle domains.Variable region in streptococcal M-proteins provides stable binding with host fibrinogen for plasminogen-mediated bacterial invasion.Identification of a new exosite involved in catalytic turnover by the streptokinase-plasmin activator complex during human plasminogen activation.Identification through combinatorial random and rational mutagenesis of a substrate-interacting exosite in the gamma domain of streptokinase.Multilocus sequence typing of Streptococcus uberis provides sensitive and epidemiologically relevant subtype information and reveals positive selection in the virulence gene pauA.The mechanism of a bacterial plasminogen activator intermediate between streptokinase and staphylokinase.Theoretical tests of the mechanical protection strategy in protein nanomechanics.Domain truncation studies reveal that the streptokinase-plasmin activator complex utilizes long range protein-protein interactions with macromolecular substrate to maximize catalytic turnover.
P2860
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P2860
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Crystal structure of streptokinase beta-domain
@ast
Crystal structure of streptokinase beta-domain
@en
Crystal structure of streptokinase beta-domain
@nl
type
label
Crystal structure of streptokinase beta-domain
@ast
Crystal structure of streptokinase beta-domain
@en
Crystal structure of streptokinase beta-domain
@nl
prefLabel
Crystal structure of streptokinase beta-domain
@ast
Crystal structure of streptokinase beta-domain
@en
Crystal structure of streptokinase beta-domain
@nl
P2093
P2860
P1433
P1476
Crystal structure of streptokinase beta-domain
@en
P2093
P2860
P356
10.1016/S0014-5793(99)01214-4
P407
P577
1999-10-01T00:00:00Z