How a protein generates a catalytic radical from coenzyme B(12): X-ray structure of a diol-dehydratase-adeninylpentylcobalamin complex
about
Crystal structure of biotin synthase, an S-adenosylmethionine-dependent radical enzymeKey enzymes catalyzing glycerol to 1,3-propanediolRadical Shuttling in a Protein: Ribose Pseudorotation Controls Alkyl-Radical Transfer in the Coenzyme B(12) Dependent Enzyme Glutamate MutaseThe crystal structure of coenzyme B12-dependent glycerol dehydratase in complex with cobalamin and propane-1,2-diolStructural rationalization for the lack of stereospecificity in coenzyme B12-dependent diol dehydrataseLarge-scale Domain Dynamics and Adenosylcobalamin Reorientation Orchestrate Radical Catalysis in Ornithine 4,5-AminomutaseCrystal Structures of Ethanolamine Ammonia-lyase Complexed with Coenzyme B12 Analogs and SubstratesRedesign of coenzyme B(12) dependent diol dehydratase to be resistant to the mechanism-based inactivation by glycerol and act on longer chain 1,2-diolsElucidating factors important for monovalent cation selectivity in enzymes: E. coli β-galactosidase as a modelData mining of iron(II) and iron(III) bond-valence parameters, and their relevance for macromolecular crystallography.Photolysis of adenosylcobalamin and radical pair recombination in ethanolamine ammonia-lyase probed on the micro- to millisecond time scale by using time-resolved optical absorption spectroscopy.A mechanochemical switch to control radical intermediates.Adenosyl radical: reagent and catalyst in enzyme reactions.Enzymatic functionalization of carbon-hydrogen bonds.Enzymatic radical catalysis: coenzyme B12-dependent diol dehydratase.Cobalamin- and corrinoid-dependent enzymesThe positions of radical intermediates in the active sites of adenosylcobalamin-dependent enzymes.Cloning, Expression, Mutagenesis Library Construction of Glycerol Dehydratase, and Binding Mode Simulation of Its Reactivase with Ligands.Coupling of hydrogenic tunneling to active-site motion in the hydrogen radical transfer catalyzed by a coenzyme B12-dependent mutase.The thiostrepton A tryptophan methyltransferase TsrM catalyses a cob(II)alamin-dependent methyl transfer reaction.Structural Basis for Substrate Specificity in Adenosylcobalamin-dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases.Structural diversity in the AdoMet radical enzyme superfamily.Dioldehydrase: an essential role for potassium ion in the homolytic cleavage of the cobalt-carbon bond in adenosylcobalamin.Crystallographic studies on B12 binding proteins in eukaryotes and prokaryotes.Vitamin B12-derivatives-enzyme cofactors and ligands of proteins and nucleic acids.Adenosylcobalamin enzymes: theory and experiment begin to convergeMolecular architectures and functions of radical enzymes and their (re)activating proteins.Analysis of the Cob(II)alamin-5'-deoxy-3',4'-anhydroadenosyl radical triplet spin system in the active site of diol dehydrase.Homocoenzyme B12 and bishomocoenzyme B12: covalent structural mimics for homolyzed, enzyme-bound coenzyme B12.Kinetic and thermodynamic studies on ligand substitution reactions and base-on/base-off equilibria of cyanoimidazolylcobamide, a vitamin B12 analog with an imidazole axial nucleoside.Roles of adenine anchoring and ion pairing at the coenzyme B12-binding site in diol dehydratase catalysis.Cobalt tetradehydrocorrins coordinated by imidazolate-like histidine in the heme pocket of horseradish peroxidase.Development of CHARMM-Compatible Force-Field Parameters for Cobalamin and Related Cofactors from Quantum Mechanical Calculations.Survey of catalytic residues and essential roles of glutamate-alpha170 and aspartate-alpha335 in coenzyme B12-dependent diol dehydratase.Homoadenosylcobalamins as probes for exploring the active sites of coenzyme B12-dependent diol dehydratase and ethanolamine ammonia-lyase.Analyses of cobalt–ligand and potassium–ligand bond lengths in metalloproteins: trends and patterns
P2860
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P2860
How a protein generates a catalytic radical from coenzyme B(12): X-ray structure of a diol-dehydratase-adeninylpentylcobalamin complex
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
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name
How a protein generates a cata ...... deninylpentylcobalamin complex
@ast
How a protein generates a cata ...... deninylpentylcobalamin complex
@en
How a protein generates a cata ...... deninylpentylcobalamin complex
@nl
type
label
How a protein generates a cata ...... deninylpentylcobalamin complex
@ast
How a protein generates a cata ...... deninylpentylcobalamin complex
@en
How a protein generates a cata ...... deninylpentylcobalamin complex
@nl
prefLabel
How a protein generates a cata ...... deninylpentylcobalamin complex
@ast
How a protein generates a cata ...... deninylpentylcobalamin complex
@en
How a protein generates a cata ...... deninylpentylcobalamin complex
@nl
P2093
P1433
P1476
How a protein generates a cata ...... deninylpentylcobalamin complex
@en
P2093
P304
P356
10.1016/S0969-2126(00)00164-7
P577
2000-07-15T00:00:00Z