Structures of active and latent PAI-1: a possible stabilizing role for chloride ions
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Specificity of binding of the low density lipoprotein receptor-related protein to different conformational states of the clade E serpins plasminogen activator inhibitor-1 and proteinase nexin-1An overview of the serpin superfamilyDistal hinge of plasminogen activator inhibitor-1 involves its latency transition and specificities toward serine proteasesPlasminogen Activator Inhibitor-1 in Cancer: Rationale and Insight for Future Therapeutic TestingCrystal structure of the complex of plasminogen activator inhibitor 2 with a peptide mimicking the reactive center loopCorticosteroid-binding globulin, a structural basis for steroid transport and proteinase-triggered releaseHigh-resolution structure of the stable plasminogen activator inhibitor type-1 variant 14-1B in its proteinase-cleaved form: A new tool for detailed interaction studies and modelingStructural Basis for Recognition of Urokinase-type Plasminogen Activator by Plasminogen Activator Inhibitor-1Crystal structure of native Anopheles gambiae serpin-2, a negative regulator of melanization in mosquitoesCrystal Structure of Plasminogen Activator Inhibitor-1 in an Active Conformation with Normal Thermodynamic StabilityCharacterization of a Small Molecule Inhibitor of Plasminogen Activator Inhibitor Type 1 That Accelerates the Transition into the Latent ConformationCrystal structure of cleaved vaspin (serpinA12)Structural gymnastics of multifunctional metamorphic proteins.Inhibition of plasminogen activator inhibitor-1 binding to endocytosis receptors of the low-density-lipoprotein receptor family by a peptide isolated from a phage display library.Collapse of a long axis: single-molecule Förster resonance energy transfer and serpin equilibrium unfolding.Serpin latency transition at atomic resolutionThe molecular basis for anti-proteolytic and non-proteolytic functions of plasminogen activator inhibitor type-1: roles of the reactive centre loop, the shutter region, the flexible joint region and the small serpin fragment.Functional and dysfunctional conformers of human neuroserpin characterized by optical spectroscopies and Molecular DynamicsCrystal Structure of the Michaelis Complex between Tissue-type Plasminogen Activator and Plasminogen Activators Inhibitor-1.Structural basis of specific inhibition of tissue-type plasminogen activator by plasminogen activators inhibitor-1Serpins in thrombosis, hemostasis and fibrinolysisSmoothing a rugged protein folding landscape by sequence-based redesign.Conformational preludes to the latency transition in PAI-1 as determined by atomistic computer simulations and hydrogen/deuterium-exchange mass spectrometry.Distinct encounter complexes of PAI-1 with plasminogen activators and vitronectin revealed by changes in the conformation and dynamics of the reactive center loop.A deletion mutant of vitronectin lacking the somatomedin B domain exhibits residual plasminogen activator inhibitor-1-binding activityA peptide mimicking the C-terminal part of the reactive center loop induces the transition to the latent form of plasminogen activator inhibitor type-1.Metals affect the structure and activity of human plasminogen activator inhibitor-1. I. Modulation of stability and protease inhibitionPlasminogen activator inhibitor-1 polymers, induced by inactivating amphipathic organochemical ligands.Resolving distinct molecular origins for copper effects on PAI-1.Characterization of a site on PAI-1 that binds to vitronectin outside of the somatomedin B domain.Metals affect the structure and activity of human plasminogen activator inhibitor-1. II. Binding affinity and conformational changes.Importance of the amino-acid composition of the shutter region of plasminogen activator inhibitor-1 for its transitions to latent and substrate forms.Mapping of the epitope of a monoclonal antibody protecting plasminogen activator inhibitor-1 against inactivating agents.Mutational analysis of plasminogen activator inhibitor-1.Serpine1 Knockdown Enhances MMP Activity after Flexor Tendon Injury in Mice: Implications for Adhesions Therapy.Functional stability of plasminogen activator inhibitor-1
P2860
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P2860
Structures of active and latent PAI-1: a possible stabilizing role for chloride ions
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Structures of active and latent PAI-1: a possible stabilizing role for chloride ions
@ast
Structures of active and latent PAI-1: a possible stabilizing role for chloride ions
@en
Structures of active and latent PAI-1: a possible stabilizing role for chloride ions
@nl
type
label
Structures of active and latent PAI-1: a possible stabilizing role for chloride ions
@ast
Structures of active and latent PAI-1: a possible stabilizing role for chloride ions
@en
Structures of active and latent PAI-1: a possible stabilizing role for chloride ions
@nl
prefLabel
Structures of active and latent PAI-1: a possible stabilizing role for chloride ions
@ast
Structures of active and latent PAI-1: a possible stabilizing role for chloride ions
@en
Structures of active and latent PAI-1: a possible stabilizing role for chloride ions
@nl
P2093
P3181
P356
P1433
P1476
Structures of active and latent PAI-1: a possible stabilizing role for chloride ions
@en
P2093
D I Buckley
D J Matthews
P304
P3181
P356
10.1021/BI000290W
P407
P50
P577
2000-07-01T00:00:00Z