Structures of prolyl oligopeptidase substrate/inhibitor complexes. Use of inhibitor binding for titration of the catalytic histidine residue
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Electrostatic effects and binding determinants in the catalysis of prolyl oligopeptidase. Site specific mutagenesis at the oxyanion binding siteSubstrate-dependent competency of the catalytic triad of prolyl oligopeptidaseStructures of the tricorn-interacting aminopeptidase F1 with different ligands explain its catalytic mechanism.Electrostatic environment at the active site of prolyl oligopeptidase is highly influential during substrate bindingDipeptidyl Aminopeptidase IV from Stenotrophomonas maltophilia Exhibits Activity against a Substrate Containing a 4-Hydroxyproline ResidueStructure and Catalysis of Acylaminoacyl Peptidase: CLOSED AND OPEN SUBUNITS OF A DIMER OLIGOPEPTIDASECatalytically distinct states captured in a crystal lattice: the substrate-bound and scavenger states of acylaminoacyl peptidase and their implications for functionalityStructural evidence of intramolecular propeptide inhibition of the aspzincin metalloendopeptidase AsaP1Kinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine familyExploration of the one-bead one-compound methodology for the design of prolyl oligopeptidase substratesMolecular dynamics study of prolyl oligopeptidase with inhibitor in binding cavity.How the Same Core Catalytic Machinery Catalyzes 17 Different Reactions: the Serine-Histidine-Aspartate Catalytic Triad of α/β-Hydrolase Fold Enzymes.Structural and mechanistic analysis of two prolyl endopeptidases: role of interdomain dynamics in catalysis and specificity.Substrate recognition properties of oligopeptidase B from Salmonella enterica serovar Typhimurium.Peptide macrocyclization catalyzed by a prolyl oligopeptidase involved in α-amanitin biosynthesis.Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV.Attacking the multi-tiered proteolytic pathology of COPD: new insights from basic and translational studies.Identification of the reactive cysteine residues in oligopeptidase B from Trypanosoma brucei.Comparative biochemical analysis of three bacterial prolyl endopeptidases: implications for coeliac sprue.Unveiling prolyl oligopeptidase ligand migration by comprehensive computational techniques.Kinetic Landscape of a Peptide Bond-Forming Prolyl Oligopeptidase.Mechanism of Action of Prolyl Oligopeptidase (PREP) in Degenerative Brain Diseases: Has Peptidase Activity Only a Modulatory Role on the Interactions of PREP with Proteins?Selective Homogeneous Assay for Circulating Endopeptidase Fibroblast Activation Protein (FAP).Dynamics and ligand-induced conformational changes in human prolyl oligopeptidase analyzed by hydrogen/deuterium exchange mass spectrometryCharacterization of a dual function macrocyclase enables design and use of efficient macrocyclization substrates.Properties of the prolyl oligopeptidase homologue from Pyrococcus furiosus.A new side opening on prolyl oligopeptidase revealed by electron microscopy.Peptide substrate profiling defines fibroblast activation protein as an endopeptidase of strict Gly(2)-Pro(1)-cleaving specificity.Ligand-induced conformational changes in prolyl oligopeptidase: a kinetic approach.Discrimination of esterase and peptidase activities of acylaminoacyl peptidase from hyperthermophilic Aeropyrum pernix K1 by a single mutation.The solution of nitrogen inversion in amidases.
P2860
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P2860
Structures of prolyl oligopeptidase substrate/inhibitor complexes. Use of inhibitor binding for titration of the catalytic histidine residue
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Structures of prolyl oligopept ...... he catalytic histidine residue
@ast
Structures of prolyl oligopept ...... he catalytic histidine residue
@en
Structures of prolyl oligopept ...... he catalytic histidine residue
@nl
type
label
Structures of prolyl oligopept ...... he catalytic histidine residue
@ast
Structures of prolyl oligopept ...... he catalytic histidine residue
@en
Structures of prolyl oligopept ...... he catalytic histidine residue
@nl
prefLabel
Structures of prolyl oligopept ...... he catalytic histidine residue
@ast
Structures of prolyl oligopept ...... he catalytic histidine residue
@en
Structures of prolyl oligopept ...... he catalytic histidine residue
@nl
P2093
P2860
P356
P1476
Structures of prolyl oligopept ...... he catalytic histidine residue
@en
P2093
P2860
P304
P356
10.1074/JBC.M007003200
P407
P577
2001-01-12T00:00:00Z