X-ray crystal structure and catalytic properties of Thr252Ile mutant of cytochrome P450cam: roles of Thr252 and water in the active center
about
The critical role of substrate-protein hydrogen bonding in the control of regioselective hydroxylation in p450cinWater oxidation by a cytochrome p450: mechanism and function of the reaction.Explicit water near the catalytic I helix Thr in the predicted solution structure of CYP2A4.New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme.QSAR of cytochrome inhibitors.Diversity of P450 enzymes in the biosynthesis of natural productsSpectroscopic studies of the cytochrome P450 reaction mechanisms.NMR study on the structural changes of cytochrome P450cam upon the complex formation with putidaredoxin. Functional significance of the putidaredoxin-induced structural changes.The proton transfer step catalyzed by yeast pyruvate kinase.Refolding processes of cytochrome P450cam from ferric and ferrous acid forms to the native conformation. Formations of folding intermediates with non-native heme coordination state.L358P mutation on cytochrome P450cam simulates structural changes upon putidaredoxin binding: the structural changes trigger electron transfer to oxy-P450cam from electron donors.QSAR studies of CYP2D6 inhibitor aryloxypropanolamines using 2D and 3D descriptors.The role of the conserved threonine in P450 BM3 oxygen activation: substrate-determined hydroxylation activity of the Thr268Ala mutant.
P2860
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P2860
X-ray crystal structure and catalytic properties of Thr252Ile mutant of cytochrome P450cam: roles of Thr252 and water in the active center
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
X-ray crystal structure and ca ...... and water in the active center
@ast
X-ray crystal structure and ca ...... and water in the active center
@en
X-ray crystal structure and ca ...... and water in the active center
@nl
type
label
X-ray crystal structure and ca ...... and water in the active center
@ast
X-ray crystal structure and ca ...... and water in the active center
@en
X-ray crystal structure and ca ...... and water in the active center
@nl
prefLabel
X-ray crystal structure and ca ...... and water in the active center
@ast
X-ray crystal structure and ca ...... and water in the active center
@en
X-ray crystal structure and ca ...... and water in the active center
@nl
P2093
P1476
X-ray crystal structure and ca ...... and water in the active center
@en
P2093
Y Ishimura
Y Kanamori
P304
P356
10.1093/OXFORDJOURNALS.JBCHEM.A022848
P577
2000-12-01T00:00:00Z