Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity
about
3′-Intercalation of a N 2 -dG 1 R - trans - anti -Benzo[ c ]phenanthrene DNA Adduct in an Iterated (CG) 3 RepeatNuclear Magnetic Resonance Solution Structure of an N 2 -Guanine DNA Adduct Derived from the Potent Tumorigen Dibenzo[ a , l ]pyrene: Intercalation from the Minor Groove with Ruptured Watson–Crick Base PairingNuclear Magnetic Resonance Studies of an N 2 -Guanine Adduct Derived from the Tumorigen Dibenzo[ a , l ]pyrene in DNA: Impact of Adduct Stereochemistry, Size, and Local DNA Sequence on Solution ConformationsHighly diastereoselective synthesis of nucleoside adducts from the carcinogenic benzo[a]pyrene diol epoxide and a computational analysis.Synthesis of oligonucleotides containing the N2-deoxyguanosine adduct of the dietary carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline.Structure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic featuresDynamic conformational heterogeneities of carcinogen-DNA adducts and their mutagenic relevance.Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement.Conformational searches elucidate effects of stereochemistry on structures of deoxyadenosine covalently bound to tumorigenic metabolites of benzo[C] phenanthrene.Adenine-DNA adducts derived from the highly tumorigenic Dibenzo[a,l]pyrene are resistant to nucleotide excision repair while guanine adducts are notDNA adduct structure-function relationships: comparing solution with polymerase structures.DNA synthesis inhibition in response to benzo[a]pyrene dihydrodiol epoxide is associated with attenuation of p(34)cdc2: Role of p53.Genetic polymorphisms of phase I metabolizing enzyme genes, their interaction with lifetime grilled and smoked meat intake, and breast cancer incidence.Different effects on human topoisomerase I by minor groove and intercalated deoxyguanosine adducts derived from two polycyclic aromatic hydrocarbon diol epoxides at or near a normal cleavage site.Repair-Resistant DNA Lesions.Polycyclic Aromatic Hydrocarbons In Edible Mushrooms from Niger Delta, Nigeria: Carcinogenic and Non-Carcinogenic Health Risk AssessmentBenzo[c]phenanthrene adducts and nogalamycin inhibit DNA transesterification by vaccinia topoisomerase.Effect of bulky lesions on DNA: solution structure of a DNA duplex containing a cholesterol adduct.DNA damage and adduct formation in immune organs of developing chicks by polycyclic aromatic hydrocarbons.
P2860
Q27650809-6CE72D90-80F0-4667-80ED-75204801AA2DQ27674954-4FAA162F-645C-4C53-BE88-7716DABEA279Q27682118-678A5F63-D05D-44E8-B12A-B7B73E187DE3Q31089397-9303DD3D-33A1-43AC-A292-5F598B9F45BBQ35111701-F519B4A2-BD2E-422D-BE67-762E99B11525Q35121667-B8DAA3A2-7EE9-4E21-842E-14661C49B8B7Q36314384-8B4CC3CC-263D-4FB0-8E45-5AB5B9211CACQ36412573-09D4AB5B-4803-4F54-9C1A-6E0CEF26E204Q36420875-9385B4E3-F8FB-4B3E-B9BF-8465D8990774Q36912161-44D05E17-F16F-4BFE-9194-32FB92187D45Q37021190-CAC1205B-29A7-45FD-B51C-8BDBF6D4982EQ37095206-0E015055-5C3E-4856-A58D-F2350AA63A5AQ37719953-2FA9ABB4-B93A-4C98-ACAC-980839660F3EQ38292238-A307AED5-CEEF-491C-A24E-0BD6CD586888Q41508281-09029C36-C9E9-45FA-9640-1E6A2C6018CDQ42129169-5B9C373C-0845-4F00-9B2C-1DFF0697BCE2Q44814637-AB5A0438-17F1-4287-AF6D-7CFE50D1C44EQ44816881-3350233A-10BF-4190-926C-CCA37C7C3ACAQ52935507-037A9D40-1677-4C11-BDFA-14FA6F8CEA4D
P2860
Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Molecular topology of polycycl ...... a link to tumorigenic activity
@ast
Molecular topology of polycycl ...... a link to tumorigenic activity
@en
Molecular topology of polycycl ...... a link to tumorigenic activity
@nl
type
label
Molecular topology of polycycl ...... a link to tumorigenic activity
@ast
Molecular topology of polycycl ...... a link to tumorigenic activity
@en
Molecular topology of polycycl ...... a link to tumorigenic activity
@nl
prefLabel
Molecular topology of polycycl ...... a link to tumorigenic activity
@ast
Molecular topology of polycycl ...... a link to tumorigenic activity
@en
Molecular topology of polycycl ...... a link to tumorigenic activity
@nl
P2093
P356
P1476
Molecular topology of polycycl ...... a link to tumorigenic activity
@en
P2093
A Kolbanovskii
B E Hingerty
N E Geacintov
P304
P356
10.1006/JMBI.2001.4425
P407
P577
2001-03-09T00:00:00Z