Probing erectile function: S-(2-boronoethyl)-L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum
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Crystal structure of human arginase I at 1.29-A resolution and exploration of inhibition in the immune response.Expression, purification, assay, and crystal structure of perdeuterated human arginase IEvolution of the arginase fold and functional diversityCrystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese clusterArginase attenuates inhibitory nonadrenergic noncholinergic nerve-induced nitric oxide generation and airway smooth muscle relaxationProbing the Specificity Determinants of Amino Acid Recognition by Arginase † ‡Inhibition of human arginase I by substrate and product analogues2-Aminoimidazole Amino Acids as Inhibitors of the Binuclear Manganese Metalloenzyme Human Arginase ICrystal Structures of Complexes with Cobalt-Reconstituted Human Arginase ICrystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infectionsCrystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of SchistosomiasisSelective endothelial overexpression of arginase II induces endothelial dysfunction and hypertension and enhances atherosclerosis in miceAnandamide improves the impaired nitric oxide-mediated neurogenic relaxation of the corpus cavernosum in diabetic rats: involvement of cannabinoid CB1 and vanilloid VR1 receptorsThe Concise Guide to PHARMACOLOGY 2013/14: enzymes.Role of the nitric oxide-cyclic GMP pathway in regulation of vaginal blood flow.Effects of tamoxifen on vaginal blood flow and epithelial morphology in the ratArginase II restricts host defense to Helicobacter pylori by attenuating inducible nitric oxide synthase translation in macrophagesElevated arginase I expression in rat aortic smooth muscle cells increases cell proliferation.Slow and sustained nitric oxide releasing compounds inhibit multipotent vascular stem cell proliferation and differentiation without causing cell death.Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein S-nitrosylation and tyrosine nitration.Arginase I suppresses IL-12/IL-23p40-driven intestinal inflammation during acute schistosomiasisImmunosuppressive activity enhances central carbon metabolism and bioenergetics in myeloid-derived suppressor cells in vitro models.Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily.Amino acids, arginase and nitric oxide in vascular health.SHIP-deficient mice develop spontaneous intestinal inflammation and arginase-dependent fibrosis.Helicobacter pylori arginase mutant colonizes arginase II knockout mice.p38 mitogen-activated protein kinase is involved in arginase-II-mediated eNOS-uncoupling in obesityThe therapeutic potential of drugs targeting the arginase pathway in asthma.Endothelial dysfunction in diabetic erectile dysfunction.Secondary amines containing one aromatic nitro group: preparation, nitrosation, sustained nitric oxide release, and the synergistic effects of released nitric oxide and an arginase inhibitor on vascular smooth muscle cell proliferation.Competitive metabolism of L-arginine: arginase as a therapeutic target in asthma.Nitric oxide modulates bladder afferent nerve activity in the in vitro urinary bladder-pelvic nerve preparation from rats with cyclophosphamide induced cystitis.Arginase: the emerging therapeutic target for vascular oxidative stress and inflammation.Nitric oxide-mediated suppression of detrusor overactivity by arginase inhibitor in rats with chronic spinal cord injury.Arginase and vascular aging.Development of novel arginase inhibitors for therapy of endothelial dysfunctionThe vascular effects of different arginase inhibitors in rat isolated aorta and mesenteric arteries.Activated Rho kinase mediates diabetes-induced elevation of vascular arginase activation and contributes to impaired corpora cavernosa relaxation: possible involvement of p38 MAPK activationCinnamide Derivatives as Mammalian Arginase Inhibitors: Synthesis, Biological Evaluation and Molecular Docking.Emerging gene and stem cell therapies for the treatment of erectile dysfunction.
P2860
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P2860
Probing erectile function: S-(2-boronoethyl)-L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum
description
2001 nî lūn-bûn
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2001 թուականի Մարտին հրատարակուած գիտական յօդուած
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2001 թվականի մարտին հրատարակված գիտական հոդված
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2001年の論文
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2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Probing erectile function: S-( ...... human penile corpus cavernosum
@ast
Probing erectile function: S-( ...... human penile corpus cavernosum
@en
Probing erectile function: S-( ...... human penile corpus cavernosum
@nl
type
label
Probing erectile function: S-( ...... human penile corpus cavernosum
@ast
Probing erectile function: S-( ...... human penile corpus cavernosum
@en
Probing erectile function: S-( ...... human penile corpus cavernosum
@nl
prefLabel
Probing erectile function: S-( ...... human penile corpus cavernosum
@ast
Probing erectile function: S-( ...... human penile corpus cavernosum
@en
Probing erectile function: S-( ...... human penile corpus cavernosum
@nl
P2093
P3181
P356
P1433
P1476
Probing erectile function: S-( ...... human penile corpus cavernosum
@en
P2093
D W Christianson
D W Speicher
R F Baggio
S K Mistry
S L Harper
P304
P3181
P356
10.1021/BI002317H
P407
P577
2001-03-06T00:00:00Z