NMR solution structure of an oligonucleotide hairpin with a 2'F-ANA/RNA stem: implications for RNase H specificity toward DNA/RNA hybrid duplexes
about
2'-deoxy-2'-fluoro-beta-D-arabinonucleic acid (2'F-ANA) modified oligonucleotides (ON) effect highly efficient, and persistent, gene silencingSolution structure of an arabinonucleic acid (ANA)/RNA duplex in a chimeric hairpin: comparison with 2'-fluoro-ANA/RNA and DNA/RNA hybridsThe solution structure of a DNA*RNA duplex containing 5-propynyl U and C; comparison with 5-Me modificationsNMR solution structure of dsDNA containing a bicyclic D-arabino-configured nucleotide fixed in an O4'-endo sugar conformationNMR structure of an -L-LNA:RNA hybrid: structural implications for RNase H recognitionA conformational transition in the structure of a 2′-thiomethyl-modified DNA visualized at high resolutionDifferential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibilityImpact of sugar pucker on base pair and mispair stability.Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencingSelection of 2'-deoxy-2'-fluoroarabinonucleotide (FANA) aptamers that bind HIV-1 reverse transcriptase with picomolar affinity2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase HEnzymatic recognition of 2'-modified ribonucleoside 5'-triphosphates: towards the evolution of versatile aptamers.G-quadruplex induced stabilization by 2'-deoxy-2'-fluoro-D-arabinonucleic acids (2'F-ANA).2'-fluoro-4'-thioarabino-modified oligonucleotides: conformational switches linked to siRNA activity.Solid-phase synthesis of 2'-deoxy-2'-fluoro- beta-D-oligoarabinonucleotides (2'F-ANA) and their phosphorothioate derivatives.Influence of nucleotide modifications at the C2' position on the Hoogsteen base-paired parallel-stranded duplex of poly(A) RNA.2'β-Fluoro-Tricyclo Nucleic Acids (2'F-tc-ANA): Thermal Duplex Stability, Structural Studies, and RNase H Activation.Synthesis and biological applications of fluoro-modified nucleic acids.Substituting CF2for O4′ in Components of Nucleic Acids: Towards Systems with Reduced Propensity to Form Abasic Lesions
P2860
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P2860
NMR solution structure of an oligonucleotide hairpin with a 2'F-ANA/RNA stem: implications for RNase H specificity toward DNA/RNA hybrid duplexes
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
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2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
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2001年論文
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2001年论文
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name
NMR solution structure of an o ...... toward DNA/RNA hybrid duplexes
@ast
NMR solution structure of an o ...... toward DNA/RNA hybrid duplexes
@en
NMR solution structure of an o ...... toward DNA/RNA hybrid duplexes
@nl
type
label
NMR solution structure of an o ...... toward DNA/RNA hybrid duplexes
@ast
NMR solution structure of an o ...... toward DNA/RNA hybrid duplexes
@en
NMR solution structure of an o ...... toward DNA/RNA hybrid duplexes
@nl
prefLabel
NMR solution structure of an o ...... toward DNA/RNA hybrid duplexes
@ast
NMR solution structure of an o ...... toward DNA/RNA hybrid duplexes
@en
NMR solution structure of an o ...... toward DNA/RNA hybrid duplexes
@nl
P2093
P356
P1476
NMR solution structure of an o ...... toward DNA/RNA hybrid duplexes
@en
P2093
P304
P356
10.1021/JA003859P
P407
P577
2001-05-30T00:00:00Z