Toward a structural understanding of the dehydratase mechanism
about
Human UDP-α-D-xylose synthase and Escherichia coli ArnA conserve a conformational shunt that controls whether xylose or 4-keto-xylose is producedStructure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in 4-amino-4-deoxy-L-arabinose biosynthesisMedium- and short-chain dehydrogenase/reductase gene and protein families : the SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymesThe structural biology of enzymes involved in natural product glycosylationCrystal structure of Escherichia coli glucose-1-phosphate thymidylyltransferase (RffH) complexed with dTTP and Mg2+High resolution X-ray structure of dTDP-glucose 4,6-dehydratase from Streptomyces venezuelaeCrystal structure of a tetrameric GDP-D-mannose 4,6-dehydratase from a bacterial GDP-D-rhamnose biosynthetic pathwayCrystal structure of the enzyme CapF of Staphylococcus aureus reveals a unique architecture composed of two functional domainsCrystal structure of the capsular polysaccharide synthesizing protein CapE of Staphylococcus aureusBiosynthesis of the tunicamycin antibiotics proceeds via unique exo-glycal intermediatesUDP-glucose 4, 6-dehydratase activity plays an important role in maintaining cell wall integrity and virulence of Candida albicansIn vitro biosynthesis of UDP-N,N'-diacetylbacillosamine by enzymes of the Campylobacter jejuni general protein glycosylation systemRmlC, a C3' and C5' carbohydrate epimerase, appears to operate via an intermediate with an unusual twist boat conformationNatural-product sugar biosynthesis and enzymatic glycodiversification.Fast and automated functional classification with MED-SuMo: an application on purine-binding proteins.Identification of an L-rhamnose synthetic pathway in two nucleocytoplasmic large DNA viruses.Functional characterization of dehydratase/aminotransferase pairs from Helicobacter and Campylobacter: enzymes distinguishing the pseudaminic acid and bacillosamine biosynthetic pathways.Structural studies of FlaA1 from Helicobacter pylori reveal the mechanism for inverting 4,6-dehydratase activity.Rational proteomics V: structure-based mutagenesis has revealed key residues responsible for substrate recognition and catalysis by the dehydrogenase and isomerase activities in human 3beta-hydroxysteroid dehydrogenase/isomerase type 1Submicroscopic deletions at 13q32.1 cause congenital microcoria.Biosynthesis of UDP-4-keto-6-deoxyglucose and UDP-rhamnose in pathogenic fungi Magnaporthe grisea and Botryotinia fuckelianaIdentification of a dTDP-rhamnose biosynthetic pathway that oscillates with the molting cycle in Caenorhabditis elegansUDP-glucuronic acid decarboxylases of Bacteroides fragilis and their prevalence in bacteria.UDP-sulfoquinovose formation by Sulfolobus acidocaldarius.The position of a key tyrosine in dTDP-4-Keto-6-deoxy-D-glucose-5-epimerase (EvaD) alters the substrate profile for this RmlC-like enzyme.Synthesis and evaluation of mimetics of UDP and UDP-alpha-D-galactose, dTDP and dTDP-alpha-D-glucose with monosaccharides replacing the key pyrophosphate unit.Pac13 is a Small, Monomeric Dehydratase that Mediates the Formation of the 3'-Deoxy Nucleoside of Pacidamycins.Differential role of NADP+ and NADPH in the activity and structure of GDP-D-mannose 4,6-dehydratase from two chlorella viruses.Molecular Architectures of Pen and Pal: Key Enzymes Required for CMP-Pseudaminic Acid Biosynthesis in Bacillus thuringiensis.Structure of the Bacillus anthracis dTDP-l-rhamnose biosynthetic pathway enzyme: dTDP-α-d-glucose 4,6-dehydratase, RfbB.Multivariate sequence analysis reveals additional function impacting residues in the SDR superfamily.
P2860
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P2860
Toward a structural understanding of the dehydratase mechanism
description
2002 nî lūn-bûn
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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
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name
Toward a structural understanding of the dehydratase mechanism
@ast
Toward a structural understanding of the dehydratase mechanism
@en
Toward a structural understanding of the dehydratase mechanism
@nl
type
label
Toward a structural understanding of the dehydratase mechanism
@ast
Toward a structural understanding of the dehydratase mechanism
@en
Toward a structural understanding of the dehydratase mechanism
@nl
prefLabel
Toward a structural understanding of the dehydratase mechanism
@ast
Toward a structural understanding of the dehydratase mechanism
@en
Toward a structural understanding of the dehydratase mechanism
@nl
P2093
P50
P3181
P1433
P1476
Toward a structural understanding of the dehydratase mechanism
@en
P2093
Andrew G Allen
Chris Whitfield
Duncan J Maskell
Jeffrey W Gross
Marie France Giraud
Michael Graninger
Rupert C Wilmouth
Simon T M Allard
P3181
P356
10.1016/S0969-2126(01)00694-3
P407
P577
2002-01-01T00:00:00Z