Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1
about
Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivoSUMO modification of the Ets-related transcription factor ERM inhibits its transcriptional activityPost-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3BSumoylated SnoN represses transcription in a promoter-specific mannerA unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex.Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formationAn extended consensus motif enhances the specificity of substrate modification by SUMOStructure of Importin13-Ubc9 complex: nuclear import and release of a key regulator of sumoylationUbc9 acetylation modulates distinct SUMO target modification and hypoxia responseSUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycleAssociation with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors.Inhibition of DNA binding by differential sumoylation of heat shock factors.The structure of SENP1-SUMO-2 complex suggests a structural basis for discrimination between SUMO paralogues during processingSUMO protease SENP1 induces isomerization of the scissile peptide bondStructure of the Siz/PIAS SUMO E3 ligase Siz1 and determinants required for SUMO modification of PCNASUSP1 antagonizes formation of highly SUMO2/3-conjugated speciesAnalysis of human cytomegalovirus-encoded SUMO targets and temporal regulation of SUMOylation of the immediate-early proteins IE1 and IE2 during infectionPhosphorylation-facilitated sumoylation of MEF2C negatively regulates its transcriptional activitySumoylation in Synaptic Function and DysfunctionE2 enzymes: more than just middle menViral Mimicry to Usurp Ubiquitin and SUMO Host PathwaysMapping the SUMOylated landscapeAdvances in the development of SUMO specific protease (SENP) inhibitorsProtein monoubiquitination and polyubiquitination generate structural diversity to control distinct biological processesHeat shock transcription factor 1 as a therapeutic target in neurodegenerative diseasesSUMOylation in control of accurate chromosome segregation during mitosisStructure and Analysis of a Complex between SUMO and Ubc9 Illustrates Features of a Conserved E2-Ubl InteractionStructure of a SUMO-binding-motif Mimic Bound to Smt3p–Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein–E2 Complex as a Platform for Selective Interactions within a SUMO PathwayThe Intrinsic Affinity between E2 and the Cys Domain of E1 in Ubiquitin-like ModificationsStructure of a signal transduction regulator, RACK1, fromArabidopsis thalianaInsights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L ComplexCrystal Structure of UBA2ufd-Ubc9: Insights into E1-E2 Interactions in Sumo PathwaysA conserved asparagine has a structural role in ubiquitin-conjugating enzymesDeterminants of Small Ubiquitin-like Modifier 1 (SUMO1) Protein Specificity, E3 Ligase, and SUMO-RanGAP1 Binding Activities of Nucleoporin RanBP2Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3Identification of Biochemically Distinct Properties of the Small Ubiquitin-related Modifier (SUMO) Conjugation Pathway in Plasmodium falciparumThe B-box 1 dimer of human promyelocytic leukemia proteinThe SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition.
P2860
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P2860
Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Structural basis for E2-mediat ...... gating enzyme Ubc9 and RanGAP1
@ast
Structural basis for E2-mediat ...... gating enzyme Ubc9 and RanGAP1
@en
Structural basis for E2-mediat ...... gating enzyme Ubc9 and RanGAP1
@nl
type
label
Structural basis for E2-mediat ...... gating enzyme Ubc9 and RanGAP1
@ast
Structural basis for E2-mediat ...... gating enzyme Ubc9 and RanGAP1
@en
Structural basis for E2-mediat ...... gating enzyme Ubc9 and RanGAP1
@nl
prefLabel
Structural basis for E2-mediat ...... gating enzyme Ubc9 and RanGAP1
@ast
Structural basis for E2-mediat ...... gating enzyme Ubc9 and RanGAP1
@en
Structural basis for E2-mediat ...... gating enzyme Ubc9 and RanGAP1
@nl
P2093
P3181
P1433
P1476
Structural basis for E2-mediat ...... gating enzyme Ubc9 and RanGAP1
@en
P2093
Christopher D Lima
Deborah A Sampson
Michael J Matunis
Victor Bernier-Villamor
P304
P3181
P356
10.1016/S0092-8674(02)00630-X
P407
P577
2002-02-08T00:00:00Z