3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 A resolution: kinetic and molecular dynamic correlates
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Novel splice isoforms for NLGN3 and NLGN4 with possible implications in autismThe molecular basis for inhibition of BphD, a C-C bond hydrolase involved in polychlorinated biphenyls degradation: large 3-substituents prevent tautomerizationCrystal Structure of Thioflavin T Bound to the Peripheral Site of Torpedo californica Acetylcholinesterase Reveals How Thioflavin T Acts as a Sensitive Fluorescent Reporter of Ligand Binding to the Acylation SiteHuprine derivatives as sub-nanomolar human acetylcholinesterase inhibitors: from rational design to validation by X-ray crystallographyCrystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesteraseHigh-performance drug discovery: computational screening by combining docking and molecular dynamics simulationsPeripheral site acetylcholinesterase inhibitors targeting both inflammation and cholinergic dysfunction.Novel cholinesterase inhibitors as future effective drugs for the treatment of Alzheimer's disease.Targeting acetylcholinesterase to treat neurodegeneration.Inhibition of human acetyl- and butyrylcholinesterase by novel carbamates of (-)- and (+)-tetrahydrofurobenzofuran and methanobenzodioxepineNovel N-allyl/propargyl tetrahydroquinolines: Synthesis via Three-component Cationic Imino Diels-Alder Reaction, Binding Prediction, and Evaluation as Cholinesterase Inhibitors.Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer's Disease.Huprines for Alzheimer's disease drug development.Design, synthesis and multitarget biological profiling of second-generation anti-Alzheimer rhein-huprine hybrids.Recent developments in structural studies on acetylcholinesterase.Model of human butyrylcholinesterase tetramer by homology modeling and dynamics simulation.(+)-Arisugacin A--computational evidence of a dual binding site covalent inhibitor of acetylcholinesterase.Customizing scoring functions for docking.Electronic structure and PCA analysis of covalent and non-covalent acetylcholinesterase inhibitors.Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study.Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.The SQM/COSMO filter: reliable native pose identification based on the quantum-mechanical description of protein-ligand interactions and implicit COSMO solvation.
P2860
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P2860
3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 A resolution: kinetic and molecular dynamic correlates
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
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2002 թվականի մարտին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
3D structure of Torpedo califo ...... d molecular dynamic correlates
@ast
3D structure of Torpedo califo ...... d molecular dynamic correlates
@en
3D structure of Torpedo califo ...... d molecular dynamic correlates
@nl
type
label
3D structure of Torpedo califo ...... d molecular dynamic correlates
@ast
3D structure of Torpedo califo ...... d molecular dynamic correlates
@en
3D structure of Torpedo califo ...... d molecular dynamic correlates
@nl
prefLabel
3D structure of Torpedo califo ...... d molecular dynamic correlates
@ast
3D structure of Torpedo califo ...... d molecular dynamic correlates
@en
3D structure of Torpedo califo ...... d molecular dynamic correlates
@nl
P2093
P50
P3181
P356
P1433
P1476
3D structure of Torpedo califo ...... d molecular dynamic correlates
@en
P2093
P304
P3181
P356
10.1021/BI011652I
P407
P577
2002-03-01T00:00:00Z