Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation
about
Structural organization of a viral IRES depends on the integrity of the GNRA motif.Internal ribosome entry site structural motifs conserved among mammalian fibroblast growth factor 1 alternatively spliced mRNAsA cis-acting replication element in the sequence encoding the NS5B RNA-dependent RNA polymerase is required for hepatitis C virus RNA replicationCrystal structure of the HCV IRES central domain reveals strategy for start-codon positioningCis-acting RNA elements in human and animal plus-strand RNA virusesFrameshifting RNA pseudoknots: structure and mechanismTools for the automatic identification and classification of RNA base pairsA hepatitis C virus (HCV) internal ribosome entry site (IRES) domain III-IV-targeted aptamer inhibits translation by binding to an apical loop of domain IIIdThe structures of nonprotein-coding RNAs that drive internal ribosome entry site functionExploiting cis-acting replication elements to direct hepatitis C virus-dependent transgene expression.Functional analyses of RNA structures shared between the internal ribosome entry sites of hepatitis C virus and the picornavirus porcine teschovirus 1 Talfan.The dynamic nature of the four-way junction of the hepatitis C virus IRES.Inhibition of the protein kinase PKR by the internal ribosome entry site of hepatitis C virus genomic RNAMolecular virology of hepatitis C virus (HCV): 2006 updateViral Internal Ribosome Entry Site Elements: Novel Ribosome-RNA Complexes and Roles in Viral PathogenesisSearching for IRESInitiation of Protein Synthesis by Hepatitis C Virus Is Refractory to Reduced eIF2 {middle dot} GTP {middle dot} Met-tRNAiMet Ternary Complex AvailabilityStudying Hepatitis C Virus: Making the Best of a Bad VirusAnalysis of natural variants of the hepatitis C virus internal ribosome entry site reveals that primary sequence plays a key role in cap-independent translationPositional effect of mutations in 5'UTR of hepatitis C virus 4a on patients' response to therapyStructure and function of HCV IRES domainsA long-range RNA-RNA interaction between the 5' and 3' ends of the HCV genomeThe solution structure of an essential stem-loop of human telomerase RNAA General Strategy to Solve the Phase Problem in RNA CrystallographyMapping metal-binding sites in the catalytic domain of bacterial RNase P RNAAttenuation of 40S ribosomal subunit abundance differentially affects host and HCV translation and suppresses HCV replicationAptamers and the RNA world, past and presentViral IRES RNA structures and ribosome interactionsA magnesium-induced RNA conformational switch at the internal ribosome entry site of hepatitis C virus genome visualized by atomic force microscopyCryo-EM structure of Hepatitis C virus IRES bound to the human ribosome at 3.9-Å resolution.Re-analysis of cryoEM data on HCV IRES bound to 40S subunit of human ribosome integrated with recent structural information suggests new contact regions between ribosomal proteins and HCV RNAIsolation and identification of short nucleotide sequences that affect translation initiation in Saccharomyces cerevisiae.Soaking Hexammine Cations into RNA Crystals to Obtain Derivatives for Phasing Diffraction DataComputational approaches toward the design of pools for the in vitro selection of complex aptamers.A loop 2 cytidine-stem 1 minor groove interaction as a positive determinant for pseudoknot-stimulated -1 ribosomal frameshiftingToward a structural understanding of IRES RNA functionNew molecular engineering approaches for crystallographic studies of large RNAsHepatitis C virus translation inhibitors targeting the internal ribosomal entry site.Distinct regions of human eIF3 are sufficient for binding to the HCV IRES and the 40S ribosomal subunit.Hepatitis C virus translation preferentially depends on active RNA replication.
P2860
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P2860
Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Crystal structure of an RNA te ...... ediated translation initiation
@ast
Crystal structure of an RNA te ...... ediated translation initiation
@en
Crystal structure of an RNA te ...... ediated translation initiation
@nl
type
label
Crystal structure of an RNA te ...... ediated translation initiation
@ast
Crystal structure of an RNA te ...... ediated translation initiation
@en
Crystal structure of an RNA te ...... ediated translation initiation
@nl
prefLabel
Crystal structure of an RNA te ...... ediated translation initiation
@ast
Crystal structure of an RNA te ...... ediated translation initiation
@en
Crystal structure of an RNA te ...... ediated translation initiation
@nl
P2093
P356
P1476
Crystal structure of an RNA te ...... ediated translation initiation
@en
P2093
Angie Grech
Jeffrey S Kieft
Kaihong Zhou
Ronald Jubin
P2888
P356
10.1038/NSB781
P577
2002-05-01T00:00:00Z
P5875
P6179
1014867598