Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes
about
Gram-positive bacterial superantigen outside-in signaling causes toxic shock syndromeCrystal structure of staphylococcal enterotoxin I (SEI) in complex with a human major histocompatibility complex class II moleculeStaphylococcal superantigens in colonization and diseaseStructural basis of T-cell specificity and activation by the bacterial superantigen TSST-1A Novel Loop Domain in Superantigens Extends their T Cell Receptor Recognition SiteCrystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor ChainMolecular Basis of a Million-Fold Affinity Maturation Process in a Protein–Protein InteractionCrystallographic and mutational data show that the streptococcal pyrogenic exotoxin J can use a common binding surface for T-cell receptor binding and dimerization.Uptake and intracellular trafficking of superantigens in dendritic cells.Spatial chemical conservation of hot spot interactions in protein-protein complexes.Herpes B virus gD interaction with its human receptor--an in silico analysis approach.Clarifying the mechanism of superantigen toxicityTCRep 3D: an automated in silico approach to study the structural properties of TCR repertoires.TCR recognition of peptide/MHC class II complexes and superantigensInterplay between superantigens and immunoreceptors.The T cell receptor beta-chain second complementarity determining region loop (CDR2beta governs T cell activation and Vbeta specificity by bacterial superantigensEvaluation of a recombinant double mutant of staphylococcal enterotoxin B (SEB-H32Q/K173E) with enhanced antitumor activity effects and decreased pyrexia.Two novel superantigens found in both group A and group C Streptococcus.The zinc-dependent major histocompatibility complex class II binding site of streptococcal pyrogenic exotoxin C is critical for maximal superantigen function and toxic activity.Long-range cooperative binding effects in a T cell receptor variable domain.Control of established colon cancer xenografts using a novel humanized single chain antibody-streptococcal superantigen fusion protein targeting the 5T4 oncofetal antigen.Bacterial superantigens.Structure of Staphylococcal Enterotoxin E in Complex with TCR Defines the Role of TCR Loop Positioning in Superantigen Recognition.Crystallization and Structure Determination of Superantigens and Immune Receptor Complexes.Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor.Crystal structures of T cell receptor (beta) chains related to rheumatoid arthritis.Soluble T cell receptor Vβ domains engineered for high-affinity binding to staphylococcal or streptococcal superantigensToxins from bacteria.Staphylococcus enterotoxin profile of China isolates and the superantigenicity of some novel enterotoxins.Cytotoxicity of lymphocytes activated by superantigen toxic-shock-syndrome toxin-1 against colorectal cancer LoVo cells.CD1d-independent activation of mouse and human iNKT cells by bacterial superantigens.Nasopharyngeal infection by Streptococcus pyogenes requires superantigen-responsive Vβ-specific T cells.Nasopharyngeal Infection of Mice with Streptococcus pyogenes and In Vivo Detection of Superantigen Activity.Assessing predictions of protein-protein interaction: the CAPRI experimentA single, engineered protein therapeutic agent neutralizes exotoxins from both Staphylococcus aureus and Streptococcus pyogenes.Zinc binding and dimerization of Streptococcus pyogenes pyrogenic exotoxin C are not essential for T-cell stimulation.ICM-DISCO docking by global energy optimization with fully flexible side-chains.Assessment of blind predictions of protein-protein interactions: current status of docking methods.Protein-protein interaction site prediction based on conditional random fields.Enhanced anti-tumor immunity by superantigen-pulsed dendritic cells.
P2860
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P2860
Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Structures of two streptococca ...... of T cell signaling complexes
@ast
Structures of two streptococca ...... of T cell signaling complexes
@en
Structures of two streptococca ...... of T cell signaling complexes
@nl
type
label
Structures of two streptococca ...... of T cell signaling complexes
@ast
Structures of two streptococca ...... of T cell signaling complexes
@en
Structures of two streptococca ...... of T cell signaling complexes
@nl
prefLabel
Structures of two streptococca ...... of T cell signaling complexes
@ast
Structures of two streptococca ...... of T cell signaling complexes
@en
Structures of two streptococca ...... of T cell signaling complexes
@nl
P2093
P50
P1433
P1476
Structures of two streptococca ...... of T cell signaling complexes
@en
P2093
Andrea S Llera
José Tormo
Klaus Karjalainen
Roy A Mariuzza
P304
P356
10.1016/S0969-2126(02)00759-1
P577
2002-05-01T00:00:00Z