Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation
about
Structural evolution of the protein kinase-like superfamilyIdentification of a Dutch founder mutation in MUSK causing fetal akinesia deformation sequenceAutoinhibition of the insulin-like growth factor I receptor by the juxtamembrane regionThe cytoplasmic adaptor protein Dok7 activates the receptor tyrosine kinase MuSK via dimerizationCasein kinase 2-dependent serine phosphorylation of MuSK regulates acetylcholine receptor aggregation at the neuromuscular junctionCell signaling by receptor tyrosine kinasesErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylationDesign principles underpinning the regulatory diversity of protein kinasesStructural and biochemical evidence for an autoinhibitory role for tyrosine 984 in the juxtamembrane region of the insulin receptorCrystal structure of the ALK (anaplastic lymphoma kinase) catalytic domainAssessing the range of kinase autoinhibition mechanisms in the insulin receptor familyStructural Mechanisms Determining Inhibition of the Collagen Receptor DDR1 by Selective and Multi-Targeted Type II Kinase InhibitorsDifferential inhibitor sensitivity of anaplastic lymphoma kinase variants found in neuroblastoma.Analysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinaseMutations in MUSK causing congenital myasthenic syndrome impair MuSK-Dok-7 interactionStructure-based reassessment of the caveolin signaling model: do caveolae regulate signaling through caveolin-protein interactions?c.1810C>T polymorphism of NTRK1 gene is associated with reduced survival in neuroblastoma patients.VEGFR-1 and VEGFR-2: two non-identical twins with a unique physiognomyReceptor tyrosine kinases with intracellular pseudokinase domainsA mutation causes MuSK reduced sensitivity to agrin and congenital myasthenia.Vascular endothelial growth factor receptors: molecular mechanisms of activation and therapeutic potentials.Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases.Juxtamembrane autoinhibition in receptor tyrosine kinases.Role of extracellular matrix proteins and their receptors in the development of the vertebrate neuromuscular junctionThe insulin receptor: both a prototypical and atypical receptor tyrosine kinase.A new autoinhibited kinase conformation reveals a salt-bridge switch in kinase activation.The precise sequence of FGF receptor autophosphorylation is kinetically driven and is disrupted by oncogenic mutations.MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4.Structure and activation of MuSK, a receptor tyrosine kinase central to neuromuscular junction formation.Structural mechanisms of the agrin-LRP4-MuSK signaling pathway in neuromuscular junction differentiation.Targeting the unactivated conformations of protein kinases for small molecule drug discovery.The role of MuSK in synapse formation and neuromuscular disease.Exploring Missense Mutations in Tyrosine Kinases Implicated with Neurodegeneration.Global analysis of muscle-specific kinase signaling by quantitative phosphoproteomics.Musk Kinase Activity is Modulated By A Serine Phosphorylation Site in The Kinase LoopEvolutionary divergence in the catalytic activity of the CAM-1, ROR1 and ROR2 kinase domains.The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites with anionic lipids.Thermodynamic and structural studies of carbohydrate binding by the agrin-G3 domain.Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction.MUSK, a new target for mutations causing congenital myasthenic syndrome.
P2860
Q21145694-7F74BB4F-BA91-4257-B47B-1BE98094E7FCQ24311382-416DCD79-948A-4E2D-81F7-2DBAAF1CF872Q24313159-B16066E8-BF49-472C-9AA1-20816EF7B29AQ24337679-DB88A7B6-66C2-4D5E-B0A6-73B8DA42D6DAQ24554479-C4AAC76D-4499-4110-B600-6F786CB11EF5Q24598357-6E73598A-E747-4094-BF8D-2CDAAB8D0673Q24621754-50E9BC61-D308-4B38-98F0-BBF64FDB85F3Q27027644-82B235EA-C7D0-4AD9-85A4-A2A3D5A9F4A3Q27641040-47488454-53DE-402D-8428-97D737945964Q27663479-BD2AF42D-A85F-42F7-A2E0-6E7B8C0E55C1Q27673414-8C6514A6-CF24-4D95-8820-F812D2FEDD67Q27683558-1C4DCBF3-667F-4685-A901-BDE99C6598C8Q27851684-BBE5669F-7B74-4236-82CA-3F77CF07E802Q28507045-D87C8D71-8C56-4CEB-A143-9D226D93EE4FQ28589320-0F36AE12-A95A-4564-A09D-ACF3FF740E94Q30524349-E75049BA-8C00-4F18-95C3-8041D4365A82Q33517966-2874CF2F-59C5-4B27-A2D7-742C1D9A3B7FQ34333828-904BE314-0D63-463B-990A-B305918CCE62Q34358042-39E86297-C56B-46E3-9056-287EF6ADC262Q34551830-AE1B8F23-A64F-4C01-A92B-6F88346CF948Q35049227-693C075B-2E36-4A00-966D-1E6C0C5E9D1EQ35058437-FD921DF8-F04F-4CD1-8774-47D1E10C8C55Q35790329-0E87E781-21E3-412F-B26B-3B3F2E9AAF88Q36321503-E0C722EB-C5CA-46A7-BE28-08C4BF37A6CAQ36626691-F63D7A3C-D852-44F9-A19D-A7B354B9EA1EQ37023987-7AC9CE4D-C0D3-4B3C-A9D5-CE87D98DFB8EQ37370492-79E8BB97-E85B-44CB-8E80-7FE6035EBE7DQ37409458-866562DA-38CC-4D44-9C0B-4920B9700D6DQ37581937-4B07C7B5-14DA-4146-B33A-CA89C3316455Q38062321-FCFFF0BC-CCC6-4CF7-AAED-755F30D89B22Q38090668-D1D21B81-ED06-4A96-B14B-46ED7742AA48Q38103527-A010B9B5-8889-47B0-8D1E-749BA1EA9109Q38932729-2933C4B6-CC86-431B-91BD-4C9B6F8910C2Q38988128-8DBADED5-F559-4230-91A5-9DB6E01AA639Q39166938-6980F82E-3148-4953-A6DB-2FBE239C7956Q39755767-7511F02F-986A-45B3-B80F-6194D2492B76Q41206091-04C2CC16-8BE7-44A4-8D38-809010D13059Q41302311-D9322E31-E8F4-429D-9CA6-F563575A9754Q44471793-108D4E0B-3ACF-4596-8442-AFA1338793D4Q45116927-98375B8F-423E-4192-8065-F5DB8FDDCC25
P2860
Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation
@ast
Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation
@en
Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation
@nl
type
label
Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation
@ast
Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation
@en
Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation
@nl
prefLabel
Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation
@ast
Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation
@en
Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation
@nl
P2093
P3181
P1433
P1476
Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation
@en
P2093
Anke Watty
Jeffrey H Till
Manuel Becerra
Stevan R Hubbard
Steven J Burden
Thomas A Neubert
Yuliang Ma
P304
P3181
P356
10.1016/S0969-2126(02)00814-6
P577
2002-09-01T00:00:00Z