High resolution crystal structures of Siglec-7. Insights into ligand specificity in the Siglec family
about
The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor designLarge-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanismsStructural implications of Siglec-5-mediated sialoglycan recognitionCatalytic cycle of human glutathione reductase near 1 A resolutionSiglecs and immune regulationA structural model for binding of the serine-rich repeat adhesin GspB to host carbohydrate receptorsAtomic resolution insight into host cell recognition by Toxoplasma gondiiPILR and PILR have a siglec fold and provide the basis of binding to sialic acidSIGLEC12, a human-specific segregating (pseudo)gene, encodes a signaling molecule expressed in prostate carcinomasHuman natural killer cell receptors: insights into their molecular function and structureNegative regulation of T cell receptor signaling by Siglec-7 (p70/AIRM) and Siglec-9Glycan array screening reveals a candidate ligand for Siglec-8Structural basis of myelin-associated glycoprotein adhesion and signallingSialoside analogue arrays for rapid identification of high affinity siglec ligandsOn-chip synthesis and screening of a sialoside library yields a high affinity ligand for Siglec-7.The immunomodulating roles of glycoproteins in epithelial ovarian cancer.Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8Siglec-7 undergoes a major conformational change when complexed with the alpha(2,8)-disialylganglioside GT1b.Sialoside specificity of the siglec family assessed using novel multivalent probes: identification of potent inhibitors of myelin-associated glycoprotein.Chemical Synthesis and Evaluation of a Disialic Acid-Containing Dextran Polymer as an Inhibitor for the Interaction between Siglec 7 and Its Ligand.Sialic Acids on Varicella-Zoster Virus Glycoprotein B Are Required for Cell-Cell FusionSiglec-7 Defines a Highly Functional Natural Killer Cell Subset and Inhibits Cell-Mediated Activities.Structures of the Streptococcus sanguinis SrpA Binding Region with Human Sialoglycans Suggest Features of the Physiological Ligand.Molecular basis of human CD22 function and therapeutic targeting.Novel aspects of sialoglycan recognition by the Siglec-like domains of streptococcal SRR glycoproteins.Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site.
P2860
Q24553353-A123653E-B04D-4AD3-B376-EE6D4681F9B4Q24561895-669943D7-3295-4489-B963-E413C1FAE0F3Q24646384-0457D1E1-0FAB-43A7-9C7B-AF64DECA6795Q24650824-4FC71EC8-AAA7-44B3-9BE2-3E67C2B18096Q26992091-7C90CB4C-141E-4418-BCDA-850DD553EAE9Q27349479-7A9DFEBF-00CF-4FC0-8F85-1944DF750A69Q27644735-47AF160C-DCF7-429C-A3EE-0DDB4E7E4E10Q27683849-BBED2651-D69B-4D45-B659-82B1738E8B08Q28237131-A7E4E133-AA5A-4196-96E3-1404E6B70769Q28241698-A43D03AE-8794-4496-AF00-16C1D239FFD9Q28275490-4DF3B87A-8C67-4FB3-8BC4-8190F47CF9B8Q28295084-295F1507-B867-47AA-AF16-753DBA618587Q28593029-FD247AE9-522B-40BF-9874-A5C658B3FDF8Q33331437-AC048ED1-C0BB-425E-B880-45B6BB964BF9Q34677175-50A716A9-23CF-4C67-9333-FD7643B79375Q35077893-6DB1EF0F-E934-445C-8F0C-CDF3EEA8F687Q37126813-B46F18AD-A94C-4A42-A7D7-7EDB259BA809Q38310798-B53D2B57-82E3-4F61-9869-C6996489AE05Q38354163-BCA5BA90-5A62-4261-B106-90E1C0DD4F91Q38856537-3EC18E1F-B138-438F-B6BA-65F3D90C8E10Q38860689-5389D865-52E4-4418-98BE-1C00819FDAD9Q39677106-4DB547C2-C398-4AB8-94E0-037D4F7DB80FQ40522700-46085D99-A409-4247-821F-E40BE4236B03Q42286136-4DB6C3AB-3D72-4176-AC9F-0EB63DA205A2Q46969243-A5CC31B2-6402-4005-B89D-ED52B257DD6DQ54223571-EF541AC0-B42E-461C-A759-334917FA22F5
P2860
High resolution crystal structures of Siglec-7. Insights into ligand specificity in the Siglec family
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
High resolution crystal struct ...... ecificity in the Siglec family
@ast
High resolution crystal struct ...... ecificity in the Siglec family
@en
High resolution crystal struct ...... ecificity in the Siglec family
@nl
type
label
High resolution crystal struct ...... ecificity in the Siglec family
@ast
High resolution crystal struct ...... ecificity in the Siglec family
@en
High resolution crystal struct ...... ecificity in the Siglec family
@nl
prefLabel
High resolution crystal struct ...... ecificity in the Siglec family
@ast
High resolution crystal struct ...... ecificity in the Siglec family
@en
High resolution crystal struct ...... ecificity in the Siglec family
@nl
P2860
P356
P1476
High resolution crystal struct ...... ecificity in the Siglec family
@en
P2093
Helen Attrill
Magnus S Alphey
P2860
P304
P356
10.1074/JBC.M210602200
P407
P577
2002-11-15T00:00:00Z