Mismatch Repair in Methylated DNA: STRUCTURE AND ACTIVITY OF THE MISMATCH-SPECIFIC THYMINE GLYCOSYLASE DOMAIN OF METHYL-CpG-BINDING PROTEIN MBD4
about
The base excision repair enzyme MED1 mediates DNA damage response to antitumor drugs and is associated with mismatch repair system integrityLesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNAThymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sitesThe current state of eukaryotic DNA base damage and repairCrystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated basesCrystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognitionExcision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylationBiochemical and structural characterization of the glycosylase domain of MBD4 bound to thymine and 5-hydroxymethyuracil-containing DNACrystal Structure of Human Methyl-Binding Domain IV Glycosylase Bound to Abasic DNARole of base excision repair in maintaining the genetic and epigenetic integrity of CpG sitesMBD4 and TDG: multifaceted DNA glycosylases with ever expanding biological rolesGC content increased at CpG flanking positions of fish genes compared with sea squirt orthologs as a mechanism for reducing impact of DNA methylation.Solution structure and intramolecular exchange of methyl-cytosine binding domain protein 4 (MBD4) on DNA suggests a mechanism to scan for mCpG/TpG mismatches.Recent advances in the structural mechanisms of DNA glycosylasesThe carboxy-terminal domain of ROS1 is essential for 5-methylcytosine DNA glycosylase activityCharacterization of the Catalytic Domain of Human APOBEC3B and the Critical Structural Role for a Conserved Methionine.Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylationTen members of the Arabidopsis gene family encoding methyl-CpG-binding domain proteins are transcriptionally active and at least one, AtMBD11, is crucial for normal developmentEpigenetic modification is central to genome reprogramming in somatic cell nuclear transfer.Epigenetic reprogramming: is deamination key to active DNA demethylation?DNA base repair--recognition and initiation of catalysis.Tagging polymorphisms of methyl-CpG binding domain 4 and gastric cardiac adenocarcinoma risk in a Chinese population.Structural and mutation studies of two DNA demethylation related glycosylases: MBD4 and TDG.MBD4-mediated glycosylase activity on a chromatin template is enhanced by acetylation.A discontinuous DNA glycosylase domain in a family of enzymes that excise 5-methylcytosine.MBD4 glycosylase mediated recognition and binding of a thymine opposite to a guanine at CpG sequencesCleavage of thymine by MBD4 glycosylase
P2860
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P2860
Mismatch Repair in Methylated DNA: STRUCTURE AND ACTIVITY OF THE MISMATCH-SPECIFIC THYMINE GLYCOSYLASE DOMAIN OF METHYL-CpG-BINDING PROTEIN MBD4
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Mismatch Repair in Methylated ...... ETHYL-CpG-BINDING PROTEIN MBD4
@ast
Mismatch Repair in Methylated ...... ETHYL-CpG-BINDING PROTEIN MBD4
@en
Mismatch Repair in Methylated ...... ETHYL-CpG-BINDING PROTEIN MBD4
@nl
type
label
Mismatch Repair in Methylated ...... ETHYL-CpG-BINDING PROTEIN MBD4
@ast
Mismatch Repair in Methylated ...... ETHYL-CpG-BINDING PROTEIN MBD4
@en
Mismatch Repair in Methylated ...... ETHYL-CpG-BINDING PROTEIN MBD4
@nl
prefLabel
Mismatch Repair in Methylated ...... ETHYL-CpG-BINDING PROTEIN MBD4
@ast
Mismatch Repair in Methylated ...... ETHYL-CpG-BINDING PROTEIN MBD4
@en
Mismatch Repair in Methylated ...... ETHYL-CpG-BINDING PROTEIN MBD4
@nl
P2093
P2860
P356
P1476
Mismatch Repair in Methylated ...... ETHYL-CpG-BINDING PROTEIN MBD4
@en
P2093
Anjum Sohail
Ashok S Bhagwat
Peiying Wu
Xiaodong Cheng
Xing Zhang
P2860
P304
P356
10.1074/JBC.M210884200
P407
P577
2003-02-14T00:00:00Z