Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase
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Acetogenesis and the Wood-Ljungdahl pathway of CO(2) fixationStructural and Kinetic Evidence for an Extended Hydrogen-bonding Network in Catalysis of Methyl Group Transfer: ROLE OF AN ACTIVE SITE ASPARAGINE RESIDUE IN ACTIVATION OF METHYL TRANSFER BY METHYLTRANSFERASESInhibition and Structure of Trichomonas vaginalis Purine Nucleoside Phosphorylase with Picomolar Transition State Analogues †Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthaseStructural Basis for Catalysis by Onconasel -Enantiomers of Transition State Analogue Inhibitors Bound to Human Purine Nucleoside PhosphorylaseIdentification of an essential active-site residue in the α-D-phosphohexomutase enzyme superfamilyCatalysis of methyl group transfers involving tetrahydrofolate and B(12)The ligand binding mechanism to purine nucleoside phosphorylase elucidated via molecular dynamics and machine learning.Immucillins as antibiotics for T-cell proliferation and malaria.Remote mutations and active site dynamics correlate with catalytic properties of purine nucleoside phosphorylase.Enzyme active site interactions by Raman/FTIR, NMR, and ab initio calculationsFrom crystal to compound: structure-based antimalarial drug discovery.8-Azapurines as isosteric purine fluorescent probes for nucleic acid and enzymatic research.Energetic mapping of transition state analogue interactions with human and Plasmodium falciparum purine nucleoside phosphorylases.Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.Solution structures of purine base analogues 6-chloroguanine, 8-azaguanine and allopurinol.Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase.Transition-state analysis of S. pneumoniae 5'-methylthioadenosine nucleosidaseTheoretical study of methyl group transfer assisted by proton transfer reaction in the N-acylated imidates.The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs
P2860
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P2860
Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Atomic dissection of the hydro ...... urine nucleoside phosphorylase
@ast
Atomic dissection of the hydro ...... urine nucleoside phosphorylase
@en
Atomic dissection of the hydro ...... urine nucleoside phosphorylase
@nl
type
label
Atomic dissection of the hydro ...... urine nucleoside phosphorylase
@ast
Atomic dissection of the hydro ...... urine nucleoside phosphorylase
@en
Atomic dissection of the hydro ...... urine nucleoside phosphorylase
@nl
prefLabel
Atomic dissection of the hydro ...... urine nucleoside phosphorylase
@ast
Atomic dissection of the hydro ...... urine nucleoside phosphorylase
@en
Atomic dissection of the hydro ...... urine nucleoside phosphorylase
@nl
P2093
P50
P356
P1433
P1476
Atomic dissection of the hydro ...... urine nucleoside phosphorylase
@en
P2093
Alexander Fedorov
Greg A Kicska
Peter C Tyler
Sean M Cahill
Steven C Almo
Vern L Schramm
Wuxian Shi
P304
14489-14498
P356
10.1021/BI026636F
P407
P577
2002-12-01T00:00:00Z