The catalytic cycle of biosynthetic thiolase: a conformational journey of an acetyl group through four binding modes and two oxyanion holes
about
The sulfur atoms of the substrate CoA and the catalytic cysteine are required for a productive mode of substrate binding in bacterial biosynthetic thiolase, a thioester-dependent enzymeCrystal Structures of Xanthomonas campestris OleA Reveal Features That Promote Head-to-Head Condensation of Two Long-Chain Fatty AcidsCrystal structures of SCP2-thiolases of Trypanosomatidae, human pathogens causing widespread tropical diseases: the importance for catalysis of the cysteine of the unique HDCF loopThe crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase (T1): insight into the reaction mechanism of its thiolase and thioesterase activitiesThe SCP2-thiolase-like protein (SLP) of Trypanosoma brucei is an enzyme involved in lipid metabolismIdentification of homologs in insignificant blast hits by exploiting extrinsic gene properties.Proteome scale characterization of human S-acylated proteins in lipid raft-enriched and non-raft membranes.Mechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains.Thiolase engineering for enhanced butanol production in Clostridium acetobutylicum.FadA5 a thiolase from Mycobacterium tuberculosis: a steroid-binding pocket reveals the potential for drug development against tuberculosisCoenzyme A-free activity, crystal structure, and rational engineering of a promiscuous β-ketoacyl thiolase from Ralstonia eutropha.Polymorphism and electronic structure of polyimine and its potential significance for prebiotic chemistry on TitanA conserved catalytic residue in the ubiquitin-conjugating enzyme family.Crystallographic substrate binding studies of Leishmania mexicana SCP2-thiolase (type-2): unique features of oxyanion hole-1.Effect of nitrogen and temperature on the transcription of an ACAT gene in Isochrysis galbana.Characterization of primary structure and post-hatching increase in chicken cytosolic acetoacetyl-coA thiolase in the liver.Crystal structure of a thiolase from Escherichia coli at 1.8 Å resolution.Rational design of thiolase substrate specificity for metabolic engineering applications
P2860
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P2860
The catalytic cycle of biosynthetic thiolase: a conformational journey of an acetyl group through four binding modes and two oxyanion holes
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The catalytic cycle of biosynt ...... g modes and two oxyanion holes
@ast
The catalytic cycle of biosynt ...... g modes and two oxyanion holes
@en
The catalytic cycle of biosynt ...... g modes and two oxyanion holes
@nl
type
label
The catalytic cycle of biosynt ...... g modes and two oxyanion holes
@ast
The catalytic cycle of biosynt ...... g modes and two oxyanion holes
@en
The catalytic cycle of biosynt ...... g modes and two oxyanion holes
@nl
prefLabel
The catalytic cycle of biosynt ...... g modes and two oxyanion holes
@ast
The catalytic cycle of biosynt ...... g modes and two oxyanion holes
@en
The catalytic cycle of biosynt ...... g modes and two oxyanion holes
@nl
P356
P1433
P1476
The catalytic cycle of biosynt ...... g modes and two oxyanion holes
@en
P2093
Petri Kursula
Rik K Wierenga
P304
P356
10.1021/BI0266232
P407
P577
2002-12-31T00:00:00Z