NMR determination of the conformation of a trimethylene interstrand cross-link in an oligodeoxynucleotide duplex containing a 5'-d(GpC) motif
about
Novel enzymatic function of DNA polymerase nu in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-linksCheckpoint signaling from a single DNA interstrand crosslinkPreferential binding and structural distortion by Fe2+ at RGGG-containing DNA sequences correlates with enhanced oxidative cleavage at such sequencesStereochemistry Modulates the Stability of Reduced Interstrand Cross-Links Arising from R - and S -α-CH 3 -γ-OH-1, N 2 -Propano-2‘-deoxyguanosine in the 5‘-CpG-3‘ DNA Sequence †Differential Base Stacking Interactions Induced by Trimethylene Interstrand DNA Cross-Links in the 5′-CpG-3′ and 5′-GpC-3′ Sequence ContextsMinor Groove Orientation of the KWKK Peptide Tethered via the N-Terminal Amine to the Acrolein-Derived 1, N 2 -γ-Hydroxypropanodeoxyguanosine Lesion with a Trimethylene Linkage,Formation of a N 2 -dG: N 2 -dG Carbinolamine DNA Cross-link by the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S ) 1, N 2 -dG AdductFormation and repair of interstrand cross-links in DNADNA interstrand crosslink repair in mammalian cells: step by step.Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy.Replication-independent repair of DNA interstrand crosslinksChemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.Chemistry and structural biology of DNA damage and biological consequencesSynthesis of G-N2-(CH2)3-N2-G Trimethylene DNA Interstrand Cross-Links.Role for DNA polymerase kappa in the processing of N2-N2-guanine interstrand cross-links.Mitomycin C reduces abundance of replication forks but not rates of fork progression in primary and transformed human cells.Stereospecific formation of the (R)-gamma-hydroxytrimethylene interstrand N2-dG:N2-dG cross-link arising from the gamma-OH-1,N2-propano-2'-deoxyguanosine adduct in the 5'-CpG-3' DNA sequence.Interstrand DNA cross-links induced by alpha,beta-unsaturated aldehydes derived from lipid peroxidation and environmental sources.Replication bypass of N2-deoxyguanosine interstrand cross-links by human DNA polymerases η and ι.Furan-modified oligonucleotides for fast, high-yielding and site-selective DNA inter-strand cross-linking with non-modified complements.Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway.
P2860
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P2860
NMR determination of the conformation of a trimethylene interstrand cross-link in an oligodeoxynucleotide duplex containing a 5'-d(GpC) motif
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
NMR determination of the confo ...... x containing a 5'-d(GpC) motif
@ast
NMR determination of the confo ...... x containing a 5'-d(GpC) motif
@en
NMR determination of the confo ...... x containing a 5'-d(GpC) motif
@nl
type
label
NMR determination of the confo ...... x containing a 5'-d(GpC) motif
@ast
NMR determination of the confo ...... x containing a 5'-d(GpC) motif
@en
NMR determination of the confo ...... x containing a 5'-d(GpC) motif
@nl
prefLabel
NMR determination of the confo ...... x containing a 5'-d(GpC) motif
@ast
NMR determination of the confo ...... x containing a 5'-d(GpC) motif
@en
NMR determination of the confo ...... x containing a 5'-d(GpC) motif
@nl
P2093
P356
P1476
NMR determination of the confo ...... x containing a 5'-d(GpC) motif
@en
P2093
Constance M Harris
Gregory A Korbel
Lubomir V Nechev
Michael P Stone
Mingzhou Zhang
Patricia A Dooley
Thomas M Harris
P356
10.1021/JA0207798
P407
P577
2003-01-08T00:00:00Z