about
Three decades of beta-lactamase inhibitorsSmall molecule inhibitors of a glycoside hydrolase attenuate inducible AmpC-mediated beta-lactam resistanceStructure-based optimization of cephalothin-analogue boronic acids as β-lactamase inhibitorsComprehensive Mechanistic Analysis of Hits from High-Throughput and Docking Screens against β-LactamaseDesign, Synthesis, Crystal Structures, and Antimicrobial Activity of Sulfonamide Boronic Acids as β-Lactamase InhibitorsFragment-guided design of subnanomolar -lactamase inhibitors active in vivoDesign and Exploration of Novel Boronic Acid Inhibitors Reveals Important Interactions with a Clavulanic Acid-Resistant Sulfhydryl-Variable (SHV) β-LactamaseTargeting Class A and C Serine β-Lactamases with a Broad-Spectrum Boronic Acid DerivativeGenetic and kinetic characterization of the novel AmpC β-lactamases DHA-6 and DHA-7.Inhibition of the class C beta-lactamase from Acinetobacter spp.: insights into effective inhibitor design.New β-lactamase inhibitors: a therapeutic renaissance in an MDR world.The role of a second-shell residue in modifying substrate and inhibitor interactions in the SHV beta-lactamase: a study of ambler position Asn276.Practical methods using boronic acid compounds for identification of class C beta-lactamase-producing Klebsiella pneumoniae and Escherichia coliPermeation through the cell membrane of a boron-based β-lactamase inhibitor.Structure, function, and inhibition along the reaction coordinate of CTX-M beta-lactamases.Serendipitous discovery of α-hydroxyalkyl esters as β-lactamase substrates.Biochemical and structural analysis of inhibitors targeting the ADC-7 cephalosporinase of Acinetobacter baumannii.Exploring sequence requirements for C₃/C₄ carboxylate recognition in the Pseudomonas aeruginosa cephalosporinase: Insights into plasticity of the AmpC β-lactamase.Click Chemistry in Lead Optimization of Boronic Acids as β-Lactamase Inhibitors.Structure-based approach for identification of novel phenylboronic acids as serine-β-lactamase inhibitors.Boronic Acid Transition State Inhibitors Active against KPC and Other Class A β-Lactamases: Structure-Activity Relationships as a Guide to Inhibitor DesignA kinetic analysis of the inhibition of FOX-4 β-lactamase, a plasmid-mediated AmpC cephalosporinase, by monocyclic β-lactams and carbapenemsIn vitro and in vivo activities of novel 6-methylidene penems as beta-lactamase inhibitors.Aminoboronic acids and esters: from synthetic challenges to the discovery of unique classes of enzyme inhibitors.Fragment-based inhibitor discovery against β-lactamaseSynthesis of α-aminoboronic acids.Recent Advances in the Rational Design and Optimization of Antibacterial Agents.Exploring the potential of boronic acids as inhibitors of OXA-24/40 β-lactamase.Small-molecule inhibitors prevent the genotoxic and protumoural effects induced by colibactin-producing bacteria.Interactions of "bora-penicilloates" with serine β-lactamases and DD-peptidases(3aS,4S,6S,7aR)-Hexahydro-3a,5,5-trimethyl-2-phenyl-4,6-methano-1,3,2-benzodioxaborole.Probing active site chemistry in SHV beta-lactamase variants at Ambler position 244. Understanding unique properties of inhibitor resistance.Inhibition of Acinetobacter-Derived Cephalosporinase: Exploring the Carboxylate Recognition Site Using Novel β-Lactamase Inhibitors.The versatility of boron in biological target engagement.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Nanomolar inhibitors of AmpC beta-lactamase
@ast
Nanomolar inhibitors of AmpC beta-lactamase
@en
Nanomolar inhibitors of AmpC beta-lactamase
@nl
type
label
Nanomolar inhibitors of AmpC beta-lactamase
@ast
Nanomolar inhibitors of AmpC beta-lactamase
@en
Nanomolar inhibitors of AmpC beta-lactamase
@nl
prefLabel
Nanomolar inhibitors of AmpC beta-lactamase
@ast
Nanomolar inhibitors of AmpC beta-lactamase
@en
Nanomolar inhibitors of AmpC beta-lactamase
@nl
P2093
P356
P1476
Nanomolar inhibitors of AmpC beta-lactamase
@en
P2093
Brian K Shoichet
Emilia Caselli
Fabio Prati
Federica Morandi
Jesús Blázquez
Pamela J Focia
Stefania Morandi
P304
P356
10.1021/JA0288338
P407
P577
2003-01-22T00:00:00Z