Structural basis for specific binding of the Gads SH3 domain to an RxxK motif-containing SLP-76 peptide: a novel mode of peptide recognition
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A proposed syntax for Minimotif Semantics, version 1Efficient T-cell receptor signaling requires a high-affinity interaction between the Gads C-SH3 domain and the SLP-76 RxxK motifIdentification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arraysRegulation and function of SKAP-55 non-canonical motif binding to the SH3c domain of adhesion and degranulation-promoting adaptor proteinNovel Src homology 3 domain-binding motifs identified from proteomic screen of a Pro-rich regionExpression, refolding and crystallizations of the Grb2-like (GADS) C-terminal SH3 domain complexed with a SLP-76 motif peptideSH3 domains of Grb2 adaptor bind to PXpsiPXR motifs within the Sos1 nucleotide exchange factor in a discriminate mannerCIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptorsRegulation of Bin1 SH3 domain binding by phosphoinositidesEvolution of SH2 domains and phosphotyrosine signalling networksRegulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8·STAM complexAMSH interacts with ESCRT-0 to regulate the stability and trafficking of CXCR4SH3 domain ligand binding: What's the consensus and where's the specificity?Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domainSLP76 and SLP65: complex regulation of signalling in lymphocytes and beyondMona/Gads SH3C binding to hematopoietic progenitor kinase 1 (HPK1) combines an atypical SH3 binding motif, R/KXXK, with a classical PXXP motif embedded in a polyproline type II (PPII) helixCdc42 GTPase-activating protein (CdGAP) interacts with the SH3D domain of Intersectin through a novel basic-rich motifPhosphorylation site dynamics of early T-cell receptor signalingAssociation between SAP and FynT: Inducible SH3 domain-mediated interaction controlled by engagement of the SLAM receptorEvolution of domain-peptide interactions to coadapt specificity and affinity to functional diversitySH2 Domains Recognize Contextual Peptide Sequence Information to Determine SelectivityGrb2 carboxyl-terminal SH3 domain can bivalently associate with two ligands, in an SH3 dependent manner.Exhaustive search of linear information encoding protein-peptide recognitionA lack of peptide binding and decreased thermostability suggests that the CASKIN2 scaffolding protein SH3 domain may be vestigial.Large-Scale Screening of Preferred Interactions of Human Src Homology-3 (SH3) Domains Using Native Target Proteins as Affinity LigandsA peptide-functionalized polymer as a minimal scaffold protein to enhance cluster formation in early T cell signal transduction.The proline-rich region of 18.5 kDa myelin basic protein binds to the SH3-domain of Fyn tyrosine kinase with the aid of an upstream segment to form a dynamic complex in vitro.Development of QSAR-Improved Statistical Potential for the Structure-Based Analysis of ProteinPeptide Binding Affinities.A graph kernel approach for alignment-free domain-peptide interaction prediction with an application to human SH3 domainsCompetitive binding of UBPY and ubiquitin to the STAM2 SH3 domain revealed by NMR.Interfacial water molecules in SH3 interactions: Getting the full picture on polyproline recognition by protein-protein interaction domains.Importance of CH/π hydrogen bonds in recognition of the core motif in proline-recognition domains: an ab initio fragment molecular orbital study.Specificity and versatility of SH3 and other proline-recognition domains: structural basis and implications for cellular signal transductionComplex role of collybistin and gephyrin in GABAA receptor clustering.In vivo significance of ITK-SLP-76 interaction in cytokine production.An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment.Titin as a giant scaffold for integrating stress and Src homology domain 3-mediated signaling pathways: the clustering of novel overlap ligand motifs in the elastic PEVK segment.Structural basis for recognition of the T cell adaptor protein SLP-76 by the SH3 domain of phospholipase Cgamma1Interactions between Cdc42 and the scaffold protein Scd2: requirement of SH3 domains for GTPase binding.Atypical recognition consensus of CIN85/SETA/Ruk SH3 domains revealed by target-assisted iterative screening.
P2860
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P2860
Structural basis for specific binding of the Gads SH3 domain to an RxxK motif-containing SLP-76 peptide: a novel mode of peptide recognition
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
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Structural basis for specific ...... el mode of peptide recognition
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Structural basis for specific ...... el mode of peptide recognition
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Structural basis for specific ...... el mode of peptide recognition
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Structural basis for specific ...... el mode of peptide recognition
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Structural basis for specific ...... el mode of peptide recognition
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Structural basis for specific ...... el mode of peptide recognition
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P2093
P3181
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P1476
Structural basis for specific ...... el mode of peptide recognition
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P2093
C Jane McGlade
Donna Berry
Piers Nash
Shawn Shun-Cheng Li
P304
P3181
P356
10.1016/S1097-2765(03)00046-7
P407
P577
2003-02-01T00:00:00Z