Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP
about
P54nrb forms a heterodimer with PSP1 that localizes to paraspeckles in an RNA-dependent manner.Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localizationThe structure of the ASAP core complex reveals the existence of a Pinin-containing PSAP complexU2AF-homology motif interactions are required for alternative splicing regulation by SPF45Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivoMammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteinsCrystal structure of a human cleavage factor CFI(m)25/CFI(m)68/RNA complex provides an insight into poly(A) site recognition and RNA loopingThe conserved RNA recognition motif 3 of U2 snRNA auxiliary factor (U2AF 65) is essential in vivo but dispensable for activity in vitroThe WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivoSAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1Splicing factors SF1 and U2AF associate in extraspliceosomal complexesU2AF homology motifs: protein recognition in the RRM worldFuzzy complexes: Specific binding without complete foldingMutations in the Caenorhabditis elegans U2AF large subunit UAF-1 alter the choice of a 3' splice site in vivoA Novel Protein-Protein Interaction in the RES (REtention and Splicing) ComplexStructure of eIF3b RNA recognition motif and its interaction with eIF3j: structural insights into the recruitment of eIF3b to the 40 S ribosomal subunitDimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60Structure of the yeast Pml1 splicing factor and its integration into the RES complexStructural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencingRaver1 Interactions with Vinculin and RNA Suggest a Feed-Forward Pathway in Directing mRNA to Focal AdhesionsNovel protein-protein contacts facilitate mRNA 3'-processing signal recognition by Rna15 and Hrp1Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognitionStructure of Phosphorylated SF1 Bound to U2AF65 in an Essential Splicing Factor ComplexStructure of Nucleophosmin DNA-binding Domain and Analysis of Its Complex with a G-quadruplex Sequence from the c-MYC PromoterStructure, dynamics and RNA binding of the multi-domain splicing factor TIA-1Cancer-relevant Splicing Factor CAPERα Engages the Essential Splicing Factor SF3b155 in a Specific Ternary ComplexCooperative structure of the heterotrimeric pre-mRNA retention and splicing complexThe Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism.RNA-binding proteins: modular design for efficient functionPhosphorylation of S776 and 14-3-3 binding modulate ataxin-1 interaction with splicing factorsSpliceosome Structure and FunctionDeletion of the N-terminus of SF2/ASF permits RS-domain-independent pre-mRNA splicing.Analysis of mutant phenotypes and splicing defects demonstrates functional collaboration between the large and small subunits of the essential splicing factor U2AF in vivo.Mutational analyses of trimethylguanosine synthase (Tgs1) and Mud2: proteins implicated in pre-mRNA splicing.The indispensable N-terminal half of eIF3j/HCR1 cooperates with its structurally conserved binding partner eIF3b/PRT1-RRM and with eIF1A in stringent AUG selectionDeficiency of splicing factor 1 suppresses the occurrence of testicular germ cell tumors.Crystal structure of a core spliceosomal protein interface.Complex spliceosomal organization ancestral to extant eukaryotes.Intrinsic disorder in the human spliceosomal proteome.
P2860
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P2860
Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP
description
2003 nî lūn-bûn
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2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Structural basis for the molec ...... ng factors U2AF65 and SF1/mBBP
@ast
Structural basis for the molec ...... ng factors U2AF65 and SF1/mBBP
@en
Structural basis for the molec ...... ng factors U2AF65 and SF1/mBBP
@nl
type
label
Structural basis for the molec ...... ng factors U2AF65 and SF1/mBBP
@ast
Structural basis for the molec ...... ng factors U2AF65 and SF1/mBBP
@en
Structural basis for the molec ...... ng factors U2AF65 and SF1/mBBP
@nl
prefLabel
Structural basis for the molec ...... ng factors U2AF65 and SF1/mBBP
@ast
Structural basis for the molec ...... ng factors U2AF65 and SF1/mBBP
@en
Structural basis for the molec ...... ng factors U2AF65 and SF1/mBBP
@nl
P2093
P3181
P1433
P1476
Structural basis for the molec ...... ng factors U2AF65 and SF1/mBBP
@en
P2093
Angela Krämer
Goran Gregorovic
Gunter Stier
Philipp Selenko
Remco Sprangers
Zakaria Rhani
P304
P3181
P356
10.1016/S1097-2765(03)00115-1
P407
P577
2003-04-01T00:00:00Z