Selective protein tyrosine phosphatase 1B inhibitors: targeting the second phosphotyrosine binding site with non-carboxylic acid-containing ligands

Selective protein tyrosine phosphatase 1B inhibitors: targeting the second phosphotyrosine binding site with non-carboxylic acid-containing ligands

Item
http://www.wikidata.org/entity/Q27641727
Druggability Assessment of Allosteric Proteins by Dynamics Simulations in the Presence of Probe MoleculesTargeting the PTPome in human disease.Protein tyrosine phosphatases: structure-function relationships.Protein tyrosine phosphatases as drug targets: strategies and challenges of inhibitor development.Protein tyrosine phosphatase structure-function relationships in regulation and pathogenesis.Fragment-based drug discovery using the SHAPES method.Potent and selective inhibition of T-cell protein tyrosine phosphatase (TCPTP) by a dinuclear copper(II) complex.Investigating the impact of Asp181 point mutations on interactions between PTP1B and phosphotyrosine substrate.Ligand efficiency indices for effective drug discovery.Novel heteroaryl phosphonicdiamides PTPs inhibitors as anti-hyperglycemic agents.Metabolic diseases drug discovery world summit. July 28-29, 2003, San Diego, CA, USA.Structure-based design of selective and potent inhibitors of protein-tyrosine phosphatase beta.Challenging the gold standard for 3D-QSAR: template CoMFA versus X-ray alignment.Computational revelation of binding mechanisms of inhibitors to endocellular protein tyrosine phosphatase 1B using molecular dynamics simulations.Effect of a novel proteoglycan PTP1B inhibitor from Ganoderma lucidum on the amelioration of hyperglycaemia and dyslipidaemia in db/db mice.Michael addition/pericyclization/rearrangement--a multicomponent strategy for the synthesis of substituted resorcinols.
P2860

Selective protein tyrosine phosphatase 1B inhibitors: targeting the second phosphotyrosine binding site with non-carboxylic acid-containing ligands

Item
http://www.wikidata.org/entity/Q27641727
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Selective protein tyrosine pho ...... oxylic acid-containing ligands
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Selective protein tyrosine pho ...... oxylic acid-containing ligands
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Selective protein tyrosine pho ...... oxylic acid-containing ligands
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type
label
Selective protein tyrosine pho ...... oxylic acid-containing ligands
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Selective protein tyrosine pho ...... oxylic acid-containing ligands
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Selective protein tyrosine pho ...... oxylic acid-containing ligands
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prefLabel
Selective protein tyrosine pho ...... oxylic acid-containing ligands
@ast
Selective protein tyrosine pho ...... oxylic acid-containing ligands
@en
Selective protein tyrosine pho ...... oxylic acid-containing ligands
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P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Selective protein tyrosine pho ...... oxylic acid-containing ligands
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P2093
P304
P31
P356
P407
P433
P478
P577
P698