Structure and mechanism of a bacterial haloalcohol dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site
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Medium- and short-chain dehydrogenase/reductase gene and protein families : the SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymesThe X-ray structure of trans-3-chloroacrylic acid dehalogenase reveals a novel hydration mechanism in the tautomerase superfamilyMapping the Reaction Coordinates of Enzymatic DefluorinationBiocatalytic and structural properties of a highly engineered halohydrin dehalogenaseCrystal structures of halohydrin hydrogen-halide-lyases from Corynebacterium sp. N-1074Structures of Proline Utilization A Reveal the Fold and Functions of the Aldehyde Dehydrogenase Superfamily Domain of Unknown FunctionRecent advances on halohydrin dehalogenases-from enzyme identification to novel biocatalytic applicationsDirected evolution strategies for enantiocomplementary haloalkane dehalogenases: from chemical waste to enantiopure building blocks.Novel dehalogenase mechanism for 2,3-dichloro-1-propanol utilization in Pseudomonas putida strain MC4.Expanding the Halohydrin Dehalogenase Enzyme Family: Identification of Novel Enzymes by Database Mining.Exploring the potential of megaprimer PCR in conjunction with orthogonal array design for mutagenesis library construction.Crystallization and preliminary X-ray crystallographic analysis of the short-chain dehydrogenase/reductase-type DDB_G0291732 protein from Dictyostelium discoideum.A high-throughput adrenaline test for the exploration of the catalytic potential of halohydrin dehalogenases in epoxide ring-opening reactions.Exploring the enantioselective mechanism of halohydrin dehalogenase from Agrobacterium radiobacter AD1 by iterative saturation mutagenesisExpanding the enzyme universe: accessing non-natural reactions by mechanism-guided directed evolution.An efficient high-throughput screening assay for rapid directed evolution of halohydrin dehalogenase for preparation of β-substituted alcohols.Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.Insight into the Mechanism of Intramolecular Inhibition of the Catalytic Activity of Sirtuin 2 (SIRT2).Key residues for controlling enantioselectivity of Halohydrin dehalogenase from Arthrobacter sp. strain AD2, revealed by structure-guided directed evolution.A robust cosolvent-compatible halohydrin dehalogenase by computational library design.Exploring the thermostable properties of halohydrin dehalogenase from Agrobacterium radiobacter AD1 by a combinatorial directed evolution strategy.Enhancing the biocatalytic manufacture of the key intermediate of atorvastatin by focused directed evolution of halohydrin dehalogenaseProperties and biotechnological applications of halohydrin dehalogenases: current state and future perspectives.Chemical and enzymatic approaches to the synthesis of optically pure ethyl (R)-4-cyano-3-hydroxybutanoate.Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse.The X-ray structure of the haloalcohol dehalogenase HheA from Arthrobacter sp. strain AD2: insight into enantioselectivity and halide binding in the haloalcohol dehalogenase family.2-Haloacrylate reductase, a novel enzyme of the medium chain dehydrogenase/reductase superfamily that catalyzes the reduction of a carbon-carbon double bond of unsaturated organohalogen compounds.Purification, gene cloning, and characterization of a novel halohydrin dehalogenase from Agromyces mediolanus ZJB120203.Expression, characterization, and improvement of a newly cloned halohydrin dehalogenase from Agrobacterium tumefaciens and its application in production of epichlorohydrin.
P2860
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P2860
Structure and mechanism of a bacterial haloalcohol dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Structure and mechanism of a b ...... ithout an NAD(P)H binding site
@ast
Structure and mechanism of a b ...... ithout an NAD(P)H binding site
@en
Structure and mechanism of a b ...... ithout an NAD(P)H binding site
@nl
type
label
Structure and mechanism of a b ...... ithout an NAD(P)H binding site
@ast
Structure and mechanism of a b ...... ithout an NAD(P)H binding site
@en
Structure and mechanism of a b ...... ithout an NAD(P)H binding site
@nl
prefLabel
Structure and mechanism of a b ...... ithout an NAD(P)H binding site
@ast
Structure and mechanism of a b ...... ithout an NAD(P)H binding site
@en
Structure and mechanism of a b ...... ithout an NAD(P)H binding site
@nl
P2093
P2860
P3181
P356
P1433
P1476
Structure and mechanism of a b ...... ithout an NAD(P)H binding site
@en
P2093
B W Dijkstra
D B Janssen
J J W Tiesinga
R M de Jong
P2860
P304
P3181
P356
10.1093/EMBOJ/CDG479
P407
P577
2003-10-01T00:00:00Z