The crystal structure of the N-terminal region of the alpha subunit of translation initiation factor 2 (eIF2alpha) from Saccharomyces cerevisiae provides a view of the loop containing serine 51, the target of the eIF2alpha-specific kinases
about
'Ribozoomin'--translation initiation from the perspective of the ribosome-bound eukaryotic initiation factors (eIFs)eIF2B is a decameric guanine nucleotide exchange factor with a γ2ε2 tetrameric core.PKR and GCN2 kinases and guanine nucleotide exchange factor eukaryotic translation initiation factor 2B (eIF2B) recognize overlapping surfaces on eIF2alphaProtein synthesis attenuation by phosphorylation of eIF2α is required for the differentiation of Trypanosoma cruzi into infective forms.Requirement for kinase-induced conformational change in eukaryotic initiation factor 2alpha (eIF2alpha) restricts phosphorylation of Ser51.Rapid evolution of protein kinase PKR alters sensitivity to viral inhibitors.An eIF2α-binding motif in protein phosphatase 1 subunit GADD34 and its viral orthologs is required to promote dephosphorylation of eIF2α.A Single Amino Acid Dictates Protein Kinase R Susceptibility to Unrelated Viral Antagonists.Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae.Protein kinase PKR mutants resistant to the poxvirus pseudosubstrate K3L protein.Residues required for phosphorylation of translation initiation factor eIF2α under diverse stress conditions are divergent between yeast and human.Parasite-specific eIF2 (eukaryotic initiation factor-2) kinase required for stress-induced translation control.Evolutionary engineering improves tolerance for medium-chain alcohols in Saccharomyces cerevisiae.
P2860
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P2860
The crystal structure of the N-terminal region of the alpha subunit of translation initiation factor 2 (eIF2alpha) from Saccharomyces cerevisiae provides a view of the loop containing serine 51, the target of the eIF2alpha-specific kinases
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2003 nî lūn-bûn
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2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2003年の論文
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2003年論文
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2003年論文
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2003年論文
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2003年論文
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2003年論文
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2003年论文
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name
The crystal structure of the N ...... the eIF2alpha-specific kinases
@ast
The crystal structure of the N ...... the eIF2alpha-specific kinases
@en
The crystal structure of the N ...... the eIF2alpha-specific kinases
@nl
type
label
The crystal structure of the N ...... the eIF2alpha-specific kinases
@ast
The crystal structure of the N ...... the eIF2alpha-specific kinases
@en
The crystal structure of the N ...... the eIF2alpha-specific kinases
@nl
prefLabel
The crystal structure of the N ...... the eIF2alpha-specific kinases
@ast
The crystal structure of the N ...... the eIF2alpha-specific kinases
@en
The crystal structure of the N ...... the eIF2alpha-specific kinases
@nl
P1476
The crystal structure of the N ...... the eIF2alpha-specific kinases
@en
P2093
David W Hoffman
Simrit Dhaliwal
P304
P407
P577
2003-11-21T00:00:00Z