Role of metals in the biological activity of Clostridium botulinum neurotoxins
about
Characterization of the metal ion binding site in the anti-terminator protein, HutP, of Bacillus subtilisEmerging opportunities for serotypes of botulinum neurotoxinsStructure- and substrate-based inhibitor design for Clostridium botulinum neurotoxin serotype ABotulinum Neurotoxin Is Shielded by NTNHA in an Interlocked ComplexReceptor binding enables botulinum neurotoxin B to sense low pH for translocation channel assembly.Monoclonal Antibodies that Inhibit the Proteolytic Activity of Botulinum Neurotoxin Serotype/B.The Translocation Domain of Botulinum Neurotoxin A Moderates the Propensity of the Catalytic Domain to Interact with Membranes at Acidic pHBotulinum neurotoxins B and E translocate at different rates and exhibit divergent responses to GT1b and low pHInhibition of catalytic activities of botulinum neurotoxin light chains of serotypes A, B and E by acetate, sulfate and calcium.Botulinum neurotoxin structure, engineering, and novel cellular trafficking and targeting.Structural and functional characterization of a calcium-activated cation channel from Tsukamurella paurometabola.Molecular structures and functional relationships in clostridial neurotoxins.Assembly and function of the botulinum neurotoxin progenitor complexThe blockade of the neurotransmitter release apparatus by botulinum neurotoxins.Comparison of extracellular and intracellular potency of botulinum neurotoxins.Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain.Double anchorage to the membrane and intact inter-chain disulfide bond are required for the low pH induced entry of tetanus and botulinum neurotoxins into neurons.Biophysical comparison of diphtheria and tetanus toxins with the formaldehyde-detoxified toxoids, the main components of diphtheria and tetanus vaccines.The structure of the tetanus toxin reveals pH-mediated domain dynamics.Engineered domain-based assays to identify individual antibodies in oligoclonal combinations targeting the same protein.
P2860
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P2860
Role of metals in the biological activity of Clostridium botulinum neurotoxins
description
2004 nî lūn-bûn
@nan
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Role of metals in the biological activity of Clostridium botulinum neurotoxins
@ast
Role of metals in the biological activity of Clostridium botulinum neurotoxins
@en
Role of metals in the biological activity of Clostridium botulinum neurotoxins
@nl
type
label
Role of metals in the biological activity of Clostridium botulinum neurotoxins
@ast
Role of metals in the biological activity of Clostridium botulinum neurotoxins
@en
Role of metals in the biological activity of Clostridium botulinum neurotoxins
@nl
prefLabel
Role of metals in the biological activity of Clostridium botulinum neurotoxins
@ast
Role of metals in the biological activity of Clostridium botulinum neurotoxins
@en
Role of metals in the biological activity of Clostridium botulinum neurotoxins
@nl
P2093
P3181
P356
P1433
P1476
Role of metals in the biological activity of Clostridium botulinum neurotoxins
@en
P2093
Desigan Kumaran
James Keller
Subramaniam Eswaramoorthy
Subramanyam Swaminathan
P304
P3181
P356
10.1021/BI035844K
P407
P577
2004-03-02T00:00:00Z