Neighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase †
about
Binding isotope effects: boon and banel -Enantiomers of Transition State Analogue Inhibitors Bound to Human Purine Nucleoside PhosphorylaseCatalytic site conformations in human PNP by 19F-NMR and crystallography.Convergent Mechanistic Features between the Structurally Diverse N- and O-Methyltransferases: Glycine N-Methyltransferase and Catechol O-Methyltransferase.Atomic detail of chemical transformation at the transition state of an enzymatic reaction.Imino-oxy acetic acid dealkylation as evidence for an inner-sphere alcohol intermediate in the reaction catalyzed by peptidylglycine alpha-hydroxylating monooxygenase.Enzymatic transition states and dynamic motion in barrier crossing.Ribocation transition state capture and rebound in human purine nucleoside phosphorylase.Four generations of transition-state analogues for human purine nucleoside phosphorylase.Pyrophosphate activation in hypoxanthine--guanine phosphoribosyltransferase with transition state analogueA synchrotron radiation study of the one-dimensional complex of sodium with (1S)-N-carboxylato-1-(9-deazaadenin-9-yl)-1,4-dideoxy-1,4-imino-D-ribitol, a member of the 'immucillin' familyTransition Path Sampling Study of the Reaction Catalyzed by Purine Nucleoside PhosphorylaseConformational dynamics in human purine nucleoside phosphorylase with reactants and transition-state analoguesFemtosecond dynamics coupled to chemical barrier crossing in a Born-Oppenheimer enzyme.A beta-fluoroamine inhibitor of purine nucleoside phosphorylaseIsotope-specific and amino acid-specific heavy atom substitutions alter barrier crossing in human purine nucleoside phosphorylaseRemote mutations and active site dynamics correlate with catalytic properties of purine nucleoside phosphorylase.Modulating Enzyme Catalysis through Mutations Designed to Alter Rapid Protein Dynamics.Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase.From crystal to compound: structure-based antimalarial drug discovery.Direct observation of multiple tautomers of oxythiamine and their recognition by the thiamine pyrophosphate riboswitch.Probing the active site of Corynebacterium callunae starch phosphorylase through the characterization of wild-type and His334-->Gly mutant enzymes.Pyrophosphate interactions at the transition states of Plasmodium falciparum and human orotate phosphoribosyltransferasesConstrained bonding environment in the Michaelis complex of Trypanosoma cruzi uridine phosphorylase.Transition-state analysis of Trypanosoma cruzi uridine phosphorylase-catalyzed arsenolysis of uridine.Immucillins in custom catalytic-site cavities.Computational mutagenesis reveals the role of active-site tyrosine in stabilising a boat conformation for the substrate: QM/MM molecular dynamics studies of wild-type and mutant xylanases.
P2860
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P2860
Neighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase †
description
2007 nî lūn-bûn
@nan
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Neighboring Group Participatio ...... ine Nucleoside Phosphorylase †
@ast
Neighboring Group Participatio ...... ine Nucleoside Phosphorylase †
@en
Neighboring Group Participatio ...... ine Nucleoside Phosphorylase †
@nl
type
label
Neighboring Group Participatio ...... ine Nucleoside Phosphorylase †
@ast
Neighboring Group Participatio ...... ine Nucleoside Phosphorylase †
@en
Neighboring Group Participatio ...... ine Nucleoside Phosphorylase †
@nl
prefLabel
Neighboring Group Participatio ...... ine Nucleoside Phosphorylase †
@ast
Neighboring Group Participatio ...... ine Nucleoside Phosphorylase †
@en
Neighboring Group Participatio ...... ine Nucleoside Phosphorylase †
@nl
P2093
P2860
P50
P356
P1433
P1476
Neighboring Group Participatio ...... ine Nucleoside Phosphorylase †
@en
P2093
Agnes Rinaldo-Matthis
Andrew S Murkin
Matthew R Birck
Wuxian Shi
P2860
P304
P356
10.1021/BI700147B
P407
P577
2007-05-01T00:00:00Z