Structure-based design of a pathway-specific nuclear import inhibitor
about
Interaction of the HIV-1 intasome with transportin 3 protein (TNPO3 or TRN-SR2)An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-AStructure of Importin13-Ubc9 complex: nuclear import and release of a key regulator of sumoylationStructural basis for the nuclear export activity of Importin13Structural basis for leucine-rich nuclear export signal recognition by CRM1ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear importConformational Heterogeneity of Karyopherinβ2 Is SegmentalStructural and energetic basis of ALS-causing mutations in the atypical proline–tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS)Crystal structure of human Karyopherin β2 bound to the PY-NLS of Saccharomyces cerevisiae Nab2A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1FUS-NLS/Transportin 1 complex structure provides insights into the nuclear targeting mechanism of FUS and the implications in ALSPhase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillizationIdentification of a karyopherin β1/β2 proline-tyrosine nuclear localization signal in huntingtin protein.Directed Differentiation of Embryonic Stem Cells Into Cardiomyocytes by Bacterial Injection of Defined Transcription FactorsDistinctive Nuclear Localization Signals in the Oomycete Phytophthora sojae.Modular organization and combinatorial energetics of proline-tyrosine nuclear localization signalsSmall molecule peptidomimetic inhibitors of importin α/β mediated nuclear transport.The molecular mechanism for nuclear transport and its application.Nuclear import by karyopherin-βs: recognition and inhibitionAn out-of-frame overlapping reading frame in the ataxin-1 coding sequence encodes a novel ataxin-1 interacting proteinFunctional and genomic analyses of alpha-solenoid proteins.Transportin-1 and Transportin-2: protein nuclear import and beyond.Recognition of nuclear targeting signals by Karyopherin-β proteins.Intermolecular masking of the HIV-1 Rev NLS by the cellular protein HIC: novel insights into the regulation of Rev nuclear import.A masked PY-NLS in Drosophila TIS11 and its mammalian homolog tristetraprolinTyrosine Phosphorylation in the C-Terminal Nuclear Localization and Retention Signal (C-NLS) of the EWS ProteinStructure and function of a spectrin-like regulator of bacterial cytokinesis.Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1.The yeast nuclear pore complex and transport through itIvermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virusNuclear transport factors: global regulation of mitosis.Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential.A study of the blue-light-dependent phosphorylation, degradation, and photobody formation of Arabidopsis CRY2.Ciliary Entry of the Hedgehog Transcriptional Activator Gli2 Is Mediated by the Nuclear Import Machinery but Differs from Nuclear Transport in Being Imp-α/β1-IndependentSec13 Regulates Expression of Specific Immune Factors Involved in Inflammation In Vivo.Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS.Probing the nuclear import signal and nuclear transport molecular determinants of PRV ICP22Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E.Peptides modeled on the RGG domain of AUF1/hnRNP-D regulate 3' UTR-dependent gene expressionNew twist to nuclear import: When two travel together
P2860
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P2860
Structure-based design of a pathway-specific nuclear import inhibitor
description
2007 nî lūn-bûn
@nan
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
name
Structure-based design of a pathway-specific nuclear import inhibitor
@ast
Structure-based design of a pathway-specific nuclear import inhibitor
@en
Structure-based design of a pathway-specific nuclear import inhibitor
@nl
type
label
Structure-based design of a pathway-specific nuclear import inhibitor
@ast
Structure-based design of a pathway-specific nuclear import inhibitor
@en
Structure-based design of a pathway-specific nuclear import inhibitor
@nl
prefLabel
Structure-based design of a pathway-specific nuclear import inhibitor
@ast
Structure-based design of a pathway-specific nuclear import inhibitor
@en
Structure-based design of a pathway-specific nuclear import inhibitor
@nl
P2093
P2860
P3181
P356
P1476
Structure-based design of a pathway-specific nuclear import inhibitor
@en
P2093
Ahmet E Cansizoglu
Beatriz M A Fontoura
Brittany J Lee
Yuh Min Chook
Zi Chao Zhang
P2860
P2888
P3181
P356
10.1038/NSMB1229
P577
2007-05-01T00:00:00Z
P5875
P6179
1031347987