Structural basis for bifunctional peptide recognition at human δ-opioid receptor
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Structure-based discovery of opioid analgesics with reduced side effects.G Protein-Coupled Receptors (GPCRs) in Alzheimer's Disease: A Focus on BACE1 Related GPCRsIn meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures.Single Amino Acid Variation Underlies Species-Specific Sensitivity to Amphibian Skin-Derived Opioid-like Peptides.Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallographyXFELs open a new era in structural chemical biologySerial femtosecond crystallography opens new avenues for Structural Biology.Serial femtosecond crystallography: A revolution in structural biology.Possibilities for serial femtosecond crystallography sample delivery at future light sources.In meso in situ serial X-ray crystallography of soluble and membrane proteinsA New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior.A novel inert crystal delivery medium for serial femtosecond crystallography.Time-resolved structural studies with serial crystallography: A new light on retinal proteins.Serial femtosecond X-ray diffraction of enveloped virus microcrystalsAtomic resolution structure determination by the cryo-EM method MicroED.Serial femtosecond crystallography datasets from G protein-coupled receptors.Serial Femtosecond Crystallography of Membrane ProteinsPreparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond CrystallographyTargeting delta opioid receptors for pain treatment: drugs in phase I and II clinical development.Serial Synchrotron X-Ray Crystallography (SSX).Further Optimization and Evaluation of Bioavailable, Mixed-Efficacy μ-Opioid Receptor (MOR) Agonists/δ-Opioid Receptor (DOR) Antagonists: Balancing MOR and DOR Affinities.Molecular Pharmacology of δ-Opioid Receptors.Proposed Mode of Binding and Action of Positive Allosteric Modulators at Opioid Receptors.A Cyclic Tetrapeptide ("Cyclodal") and Its Mirror-Image Isomer Are Both High-Affinity μ Opioid Receptor Antagonists.A Bright Future for Serial Femtosecond Crystallography with XFELs.New Technologies for Elucidating Opioid Receptor Function.Binding mode analyses of NAP derivatives as mu opioid receptor selective ligands through docking studies and molecular dynamics simulation.Crystallization of Membrane Proteins: An Overview.Hitchhiking on the heptahelical highway: structure and function of 7TM receptor complexes.Insights into the function of opioid receptors from molecular dynamics simulations of available crystal structures.New approaches towards the understanding of integral membrane proteins: A structural perspective on G protein-coupled receptors.[Dmt(1)]DALDA analogues modified with tyrosine analogues at position 1.Designing Safer Analgesics via μ-Opioid Receptor Pathways.Conformational Heterogeneity of Intracellular Loop 3 of the μ-opioid G-protein Coupled Receptor.Propagation of the Allosteric Modulation Induced by Sodium in the δ-Opioid Receptor.Opioid Receptor Activity and Analgesic Potency of DPDPE Peptide Analogues Containing a Xylene Bridge.A Structural Framework for GPCR Chemogenomics: What's In a Residue Number?Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.Fentanyl-related designer drugs W-18 and W-15 lack appreciable opioid activity in vitro and in vivo.Nanoscale clustering of the neurotrophin receptor TrkB revealed by super-resolution STED microscopy.
P2860
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P2860
Structural basis for bifunctional peptide recognition at human δ-opioid receptor
description
2015 nî lūn-bûn
@nan
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Structural basis for bifunctional peptide recognition at human δ-opioid receptor
@ast
Structural basis for bifunctional peptide recognition at human δ-opioid receptor
@en
Structural basis for bifunctional peptide recognition at human δ-opioid receptor
@nl
type
label
Structural basis for bifunctional peptide recognition at human δ-opioid receptor
@ast
Structural basis for bifunctional peptide recognition at human δ-opioid receptor
@en
Structural basis for bifunctional peptide recognition at human δ-opioid receptor
@nl
prefLabel
Structural basis for bifunctional peptide recognition at human δ-opioid receptor
@ast
Structural basis for bifunctional peptide recognition at human δ-opioid receptor
@en
Structural basis for bifunctional peptide recognition at human δ-opioid receptor
@nl
P2093
P2860
P50
P3181
P356
P1476
Structural basis for bifunctional peptide recognition at human δ-opioid receptor
@en
P2093
Andrii Ishchenko
Bryan L Roth
Cecilia Betti
Chelsie E Conrad
Chun Hong Yoon
Cornelius Gati
Dingjie Wang
Dirk Tourwé
Dominik Oberthuer
Garth J Williams
P2860
P2888
P304
P3181
P356
10.1038/NSMB.2965
P50
P577
2015-03-01T00:00:00Z
P5875
P6179
1043208053