Structural consequences of disease-causing mutations in the ATRX-DNMT3-DNMT3L (ADD) domain of the chromatin-associated protein ATRX
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The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domainHistone regulation in the CNS: basic principles of epigenetic plasticityActive DNA demethylation of the vertebrate genomes by DNA methyltransferases: deaminase, dehydroxymethylase or demethylase?Pediatric solid tumor genomics and developmental pliancyCombinatorial readout of histone H3 modifications specifies localization of ATRX to heterochromatinATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndromeThe Role of ATRX in the Alternative Lengthening of Telomeres (ALT) PhenotypeATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cellsPML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cellsComparative analysis of the ATRX promoter and 5' regulatory region reveals conserved regulatory elements which are linked to roles in neurodevelopment, alpha-globin regulation and testicular functionHow chromatin-binding modules interpret histone modifications: lessons from professional pocket pickersATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neuronsPrioritizing genes for X-linked diseases using population exome data.Decreased expression of GRAF1/OPHN-1-L in the X-linked alpha thalassemia mental retardation syndrome.Analysis of neonatal brain lacking ATRX or MeCP2 reveals changes in nucleosome density, CTCF binding and chromatin loopingThe PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrityLoss of wild-type ATRX expression in somatic cell hybrids segregates with activation of Alternative Lengthening of Telomeres.The role of genetics in the establishment and maintenance of the epigenome.A phylogenetic study of SPBP and RAI1: evolutionary conservation of chromatin binding modules.Regulating the chromatin landscape: structural and mechanistic perspectives.Role of ATRX in chromatin structure and function: implications for chromosome instability and human diseaseα-Thalassemia, mental retardation, and myelodysplastic syndrome.Nucleosome-depleted chromatin gaps recruit assembly factors for the H3.3 histone variant.Family-wide Characterization of Histone Binding Abilities of Human CW Domain-containing ProteinsMutations in DNMT3B Modify Epigenetic Repression of the D4Z4 Repeat and the Penetrance of Facioscapulohumeral Dystrophy.PHD fingers in human diseases: disorders arising from misinterpreting epigenetic marks.Molecular coupling of DNA methylation and histone methylation.ATRX: the case of a peculiar chromatin remodeler.Genetic syndromes caused by mutations in epigenetic genes.Readout of epigenetic modifications.Regulation of human cytomegalovirus transcription in latency: beyond the major immediate-early promoterEmerging roles of ATRX in cancer.A Structural Perspective on Readout of Epigenetic Histone and DNA Methylation Marks.Conservation and diversification of polycomb repressive complex 2 (PRC2) proteins in the green lineage.Allosteric control of mammalian DNA methyltransferases - a new regulatory paradigm.Domain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases.Regulation of ICP0-null mutant herpes simplex virus type 1 infection by ND10 components ATRX and hDaxx.Human cytomegalovirus protein pp71 displaces the chromatin-associated factor ATRX from nuclear domain 10 at early stages of infection.XNP/dATRX interacts with DREF in the chromatin to regulate gene expression.
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P2860
Structural consequences of disease-causing mutations in the ATRX-DNMT3-DNMT3L (ADD) domain of the chromatin-associated protein ATRX
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structural consequences of dis ...... omatin-associated protein ATRX
@ast
Structural consequences of dis ...... omatin-associated protein ATRX
@en
Structural consequences of dis ...... omatin-associated protein ATRX
@nl
type
label
Structural consequences of dis ...... omatin-associated protein ATRX
@ast
Structural consequences of dis ...... omatin-associated protein ATRX
@en
Structural consequences of dis ...... omatin-associated protein ATRX
@nl
prefLabel
Structural consequences of dis ...... omatin-associated protein ATRX
@ast
Structural consequences of dis ...... omatin-associated protein ATRX
@en
Structural consequences of dis ...... omatin-associated protein ATRX
@nl
P2093
P2860
P3181
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P1476
Structural consequences of dis ...... omatin-associated protein ATRX
@en
P2093
Anthony Argentaro
Daniela Rhodes
David Neuhaus
Ji-Chun Yang
Lynda Chapman
Monika S Kowalczyk
Richard J Gibbons
P2860
P304
P3181
P356
10.1073/PNAS.0704057104
P407
P577
2007-07-17T00:00:00Z