Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: from the active site to the second phosphotyrosine binding site

Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: from the active site to the second phosphotyrosine binding site

Item
http://www.wikidata.org/entity/Q27647407
Molecular mechanistic associations of human diseasesDiscovery of novel PTP1B inhibitors with antihyperglycemic activity.Methyl effects on protein-ligand bindingFak56 functions downstream of integrin alphaPS3betanu and suppresses MAPK activation in neuromuscular junction growthKnowledge-based characterization of similarity relationships in the human protein-tyrosine phosphatase family for rational inhibitor designProtein tyrosine phosphatases as drug targets: strategies and challenges of inhibitor development.Macrocyclization of the ATCUN motif controls metal binding and catalysis.Identification of Bidentate Salicylic Acid Inhibitors of PTP1B.Synthesis and characterization of 5,7-dihydroxyflavanone derivatives as novel protein tyrosine phosphatase 1B inhibitors.Novel Mixed-Type Inhibitors of Protein Tyrosine Phosphatase 1B. Kinetic and Computational Studies.Structural analysis of protein tyrosine phosphatase 1B reveals potentially druggable allosteric binding sites.Computational Insight into Protein Tyrosine Phosphatase 1B Inhibition: A Case Study of the Combined Ligand- and Structure-Based Approach.Design, synthesis, and biological evaluation of bromophenol derivatives as protein tyrosine phosphatase 1B inhibitors.Copolymers of novel methacrylic and styrenic monomer based on the thiophene: synthesis, characterization, monomer reactivity ratios, thermal properties, and biological activity.
P2860

Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: from the active site to the second phosphotyrosine binding site

Item
http://www.wikidata.org/entity/Q27647407
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structure-based optimization o ...... d phosphotyrosine binding site
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Structure-based optimization o ...... d phosphotyrosine binding site
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Structure-based optimization o ...... d phosphotyrosine binding site
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type
label
Structure-based optimization o ...... d phosphotyrosine binding site
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Structure-based optimization o ...... d phosphotyrosine binding site
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Structure-based optimization o ...... d phosphotyrosine binding site
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prefLabel
Structure-based optimization o ...... d phosphotyrosine binding site
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Structure-based optimization o ...... d phosphotyrosine binding site
@en
Structure-based optimization o ...... d phosphotyrosine binding site
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Structure-based optimization o ...... d phosphotyrosine binding site
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P2093
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921