Crystal structure of activin receptor type IIB kinase domain from human at 2.0 Å resolution
about
Structure of the bone morphogenetic protein receptor ALK2 and implications for fibrodysplasia ossificans progressivaOligomeric interactions of TGF-β and BMP receptorsPeptide ligands that use a novel binding site to target both TGF-β receptors.Molecular modeling and molecular dynamic simulation of the effects of variants in the TGFBR2 kinase domain as a paradigm for interpretation of variants obtained by next generation sequencing.Structural Basis of Intracellular TGF-β Signaling: Receptors and Smads.Functional validation reveals the novel missense V419L variant in TGFBR2 associated with Loeys-Dietz syndrome (LDS) impairs canonical TGF-β signalingSmall molecules dorsomorphin and LDN-193189 inhibit myostatin/GDF8 signaling and promote functional myoblast differentiation.Lysine conservation and context in TGFbeta and Wnt signaling suggest new targets and general themes for posttranslational modification.
P2860
Q24623325-5420DBBD-BB33-420C-8B82-A3CDED0064B8Q27023170-D68DDE66-E6B4-4697-B7D4-841D1C8382DEQ33708971-4C652CAD-DF5E-4027-95FF-DC9BDCE5CC4CQ36275442-86BD25BF-B75C-466F-96C0-E748BF099DADQ38934096-63979725-BF40-44FC-A0C9-2B42B66C3822Q40977010-CF790C83-A4BF-43BC-AB2F-73BFDF7DF5EEQ41761999-7F7C9463-412B-47C2-BC8B-D6DE66230168Q43120344-EB93E0B4-D4C3-43F0-8C35-ECAE4C541611
P2860
Crystal structure of activin receptor type IIB kinase domain from human at 2.0 Å resolution
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Crystal structure of activin r ...... from human at 2.0 Å resolution
@ast
Crystal structure of activin r ...... from human at 2.0 Å resolution
@en
Crystal structure of activin r ...... from human at 2.0 Å resolution
@nl
type
label
Crystal structure of activin r ...... from human at 2.0 Å resolution
@ast
Crystal structure of activin r ...... from human at 2.0 Å resolution
@en
Crystal structure of activin r ...... from human at 2.0 Å resolution
@nl
prefLabel
Crystal structure of activin r ...... from human at 2.0 Å resolution
@ast
Crystal structure of activin r ...... from human at 2.0 Å resolution
@en
Crystal structure of activin r ...... from human at 2.0 Å resolution
@nl
P2093
P2860
P356
P1433
P1476
Crystal structure of activin r ...... from human at 2.0 Å resolution
@en
P2093
Matt Griffor
Pat Loulakis
Seungil Han
P2860
P304
P356
10.1110/PS.073068407
P577
2007-10-01T00:00:00Z