Strain and near attack conformers in enzymic thiamin catalysis: X-ray crystallographic snapshots of bacterial transketolase in covalent complex with donor ketoses xylulose 5-phosphate and fructose 6-phosphate, and in noncovalent complex with accepto
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The crystal structure of human transketolase and new insights into its mode of actionSnapshots of Catalysis in the E1 Subunit of the Pyruvate Dehydrogenase Multienzyme ComplexDetection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylaseStructural Insights into the Prereaction State of Pyruvate Decarboxylase from Zymomonas mobilis ,Crystal structure of Bifidobacterium Longum phosphoketolase; key enzyme for glucose metabolism in BifidobacteriumDouble Duty for a Conserved Glutamate in Pyruvate Decarboxylase: Evidence of the Participation in Stereoelectronically Controlled Decarboxylation and in Protonation of the Nascent Carbanion/Enamine Intermediate,Crystal Structures of Phosphoketolase: THIAMINE DIPHOSPHATE-DEPENDENT DEHYDRATION MECHANISMTwisted Schiff base intermediates and substrate locale revise transaldolase mechanismStructure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzymeSub-ångström-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediateA dual conformation of the post-decarboxylation intermediate is associated with distinct enzyme states in mycobacterial KGD (α-ketoglutarate decarboxylase)A δ38 deletion variant of human transketolase as a model of transketolase-like protein 1 exhibits no enzymatic activityDiphenyl urea derivatives as inhibitors of transketolase: a structure-based virtual screening.A thermostable transketolase evolved for aliphatic aldehyde acceptors.Structural Analysis of an Evolved Transketolase Reveals Divergent Binding Modes.A preliminary X-ray study of transketolase from Burkholderia pseudomallei.Substrate Distortion and the Catalytic Reaction Mechanism of 5-Carboxyvanillate Decarboxylase.Stabilizing biocatalysts.Using site-saturation mutagenesis to explore mechanism and substrate specificity in thiamin diphosphate-dependent enzymes.Engineering stereoselectivity of ThDP-dependent enzymes.Crystallization and preliminary X-ray diffraction analysis of transaldolase from Thermoplasma acidophilum.Physiological relation between respiration activity and heterologous expression of selected benzoylformate decarboxylase variants in Escherichia coliIdentification of major zinc-binding proteins from a marine cyanobacterium: insight into metal uptake in oligotrophic environments.Phage Display on the Anti-infective Target 1-Deoxy-d-xylulose-5-phosphate Synthase Leads to an Acceptor-Substrate Competitive Peptidic Inhibitor.The Mesomeric Effect of Thiazolium on non-Kekulé Diradicals in Pichia stipitis Transketolase.Donor Promiscuity of a Thermostable Transketolase by Directed Evolution: Efficient Complementation of 1-Deoxy-d-xylulose-5-phosphate Synthase Activity.Structural and biochemical interrogation on transketolase from Pichia stipitis for new functionality.Rational substrate and enzyme engineering of transketolase for aromatics.
P2860
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P2860
Strain and near attack conformers in enzymic thiamin catalysis: X-ray crystallographic snapshots of bacterial transketolase in covalent complex with donor ketoses xylulose 5-phosphate and fructose 6-phosphate, and in noncovalent complex with accepto
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Strain and near attack conform ...... ncovalent complex with accepto
@en
Strain and near attack conform ...... ncovalent complex with accepto
@nl
type
label
Strain and near attack conform ...... ncovalent complex with accepto
@en
Strain and near attack conform ...... ncovalent complex with accepto
@nl
prefLabel
Strain and near attack conform ...... ncovalent complex with accepto
@en
Strain and near attack conform ...... ncovalent complex with accepto
@nl
P2093
P3181
P356
P1433
P1476
Strain and near attack conform ...... ptor aldose ribose 5-phosphate
@en
P2093
Christoph Parthier
Gerhard Hübner
Kai Tittmann
Manfred S Weiss
Martin Kleinschmidt
Peter Asztalos
Ralph Golbik
Rudolf Friedemann
P304
12037-12052
P3181
P356
10.1021/BI700844M
P407
P50
P577
2007-10-03T00:00:00Z