Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design
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Glutamine synthetase in Medicago truncatula, unveiling new secrets of a very old enzymeRoles of glutamine synthetase inhibition in epilepsyStructures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition MechanismThe structures of cytosolic and plastid-located glutamine synthetases fromMedicago truncatulareveal a common and dynamic architectureMinireview on Glutamine Synthetase Deficiency, an Ultra-Rare Inborn Error of Amino Acid BiosynthesisMolecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release sitep97/VCP promotes degradation of CRBN substrate glutamine synthetase and neosubstrates.Inhibition of human glutamine synthetase by L-methionine-S,R-sulfoximine-relevance to the treatment of neurological diseases.The conserved hypothetical protein Rv0574c is required for cell wall integrity, stress tolerance, and virulence of Mycobacterium tuberculosis.A sensing role of the glutamine synthetase in the nitrogen regulation network in Fusarium fujikuroiMolecular Mechanisms of Glutamine Synthetase Mutations that Lead to Clinically Relevant Pathologies.Glutamine Synthetase Drugability beyond Its Active Site: Exploring Oligomerization Interfaces and Pockets.SLC39A8 Deficiency: A Disorder of Manganese Transport and Glycosylation.Glutamine synthetase predicts adjuvant TACE response in hepatocellular carcinomaRegulation of brain glutamate metabolism by nitric oxide and S-nitrosylationGlutamine Triggers Acetylation-Dependent Degradation of Glutamine Synthetase via the Thalidomide Receptor Cereblon.Regulation of astrocyte glutamine synthetase in epilepsyGenetic determination of essential residues of the Vibrio cholerae actin cross-linking domain reveals functional similarity with glutamine synthetases.Cytoarchitecture and ultrastructure of neural stem cell niches and neurogenic complexes maintaining adult neurogenesis in the olfactory midbrain of spiny lobsters, Panulirus argus.Glutamine synthetase in legumes: recent advances in enzyme structure and functional genomics.Critical Evaluation of the Changes in Glutamine Synthetase Activity in Models of Cerebral Stroke.The relationship between serum ammonia level and neurologic complications in patients with acute glufosinate ammonium poisoning: A prospective observational study.The Glutamate-Glutamine Cycle in Epilepsy.Relationships Between Essential Manganese Biology and Manganese Toxicity in Neurological Disease.Improving the efficiency of CHO cell line generation using glutamine synthetase gene knockout cells.Secondary NAD+ deficiency in the inherited defect of glutamine synthetase.The Enzymology of 2-Hydroxyglutarate, 2-Hydroxyglutaramate and 2-Hydroxysuccinamate and Their Relationship to OncometabolitesDelivery of glutamine synthetase gene by baculovirus vectors: a proof of concept for the treatment of acute hyperammonemia.Crystallization and preliminary crystallographic characterization of glutamine synthetase from Medicago truncatula.Glutamine synthetase mutations that cause glutamine deficiency: mechanistic insights from molecular dynamics simulations.Mechanistic Basis for ATP-Dependent Inhibition of Glutamine Synthetase by Tabtoxinine-β-lactam.Hyperammonemia following glufosinate-containing herbicide poisoning: a potential marker of severe neurotoxicity.glutamate + NH4+ + ATP => glutamine + ADP + orthophosphateCharacterization of an L-phosphinothricin resistant glutamine synthetase from Exiguobacterium sp. and its improvement.Characterization and improved properties of Glutamine synthetase from Providencia vermicola by site-directed mutagenesisStructural Analysis of Glutamine Synthetase from Helicobacter pylori
P2860
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P2860
Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Crystal structures of mammalia ...... for drug and herbicide design
@ast
Crystal structures of mammalia ...... for drug and herbicide design
@en
Crystal structures of mammalia ...... for drug and herbicide design
@nl
type
label
Crystal structures of mammalia ...... for drug and herbicide design
@ast
Crystal structures of mammalia ...... for drug and herbicide design
@en
Crystal structures of mammalia ...... for drug and herbicide design
@nl
prefLabel
Crystal structures of mammalia ...... for drug and herbicide design
@ast
Crystal structures of mammalia ...... for drug and herbicide design
@en
Crystal structures of mammalia ...... for drug and herbicide design
@nl
P2093
P50
P1476
Crystal structures of mammalia ...... for drug and herbicide design
@en
P2093
Sherry L Mowbray
T Alwyn Jones
Wojciech W Krajewski
P304
P356
10.1016/J.JMB.2007.10.029
P407
P577
2008-01-04T00:00:00Z