Structural and functional analysis of the Spt16p N-terminal domain reveals overlapping roles of yFACT subunits
about
Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modificationyFACT induces global accessibility of nucleosomal DNA without H2A-H2B displacementThe FACT Spt16 “peptidase” domain is a histone H3–H4 binding moduleStructure of the Spt16 Middle Domain Reveals Functional Features of the Histone Chaperone FACTStructural basis of histone H2A-H2B recognition by the essential chaperone FACTFACT prevents the accumulation of free histones evicted from transcribed chromatin and a subsequent cell cycle delay in G1.The E2F functional analogue SBF recruits the Rpd3(L) HDAC, via Whi5 and Stb1, and the FACT chromatin reorganizer, to yeast G1 cyclin promotersA PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions.A role for Chd1 and Set2 in negatively regulating DNA replication in Saccharomyces cerevisiaeA role for FACT in repopulation of nucleosomes at inducible genesHistone chaperones link histone nuclear import and chromatin assemblyInsight into the mechanism of nucleosome reorganization from histone mutants that suppress defects in the FACT histone chaperone.FACT is a sensor of DNA torsional stress in eukaryotic cells.Mutant versions of the S. cerevisiae transcription elongation factor Spt16 define regions of Spt16 that functionally interact with histone H3FACT, the Bur kinase pathway, and the histone co-repressor HirC have overlapping nucleosome-related roles in yeast transcription elongation.The histone chaperone FACT: structural insights and mechanisms for nucleosome reorganization.Histone chaperones, histone acetylation, and the fluidity of the chromogenomeHistone chaperone FACT coordinates nucleosome interaction through multiple synergistic binding events.Histone Chaperones Spt6 and FACT: Similarities and Differences in Modes of Action at Transcribed GenesIdentification of Mutant Versions of the Spt16 Histone Chaperone That Are Defective for Transcription-Coupled Nucleosome Occupancy in Saccharomyces cerevisiae.FACT Disrupts Nucleosome Structure by Binding H2A-H2B with Conserved Peptide MotifsThe Abundant Histone Chaperones Spt6 and FACT Collaborate to Assemble, Inspect, and Maintain Chromatin Structure in Saccharomyces cerevisiae.Crystal Structure of Human SSRP1 Middle Domain Reveals a Role in DNA BindingIntegrated molecular mechanism directing nucleosome reorganization by human FACTA nucleosomal region important for ensuring proper interactions between the transcription elongation factor Spt16 and transcribed genes in Saccharomyces cerevisiae.The FACT histone chaperone guides histone H4 into its nucleosomal conformation in Saccharomyces cerevisiae.A highly conserved region within H2B is important for FACT to act on nucleosomes.Chaperoning histones during DNA replication and repair.The histone shuffle: histone chaperones in an energetic dance.The role of FACT in making and breaking nucleosomes.Structure of the human histone chaperone FACT Spt16 N-terminal domain.The histone chaperone facilitates chromatin transcription (FACT) protein maintains normal replication fork ratesRegulation of chaperone binding and nucleosome dynamics by key residues within the globular domain of histone H3.Catch me if you can: how the histone chaperone FACT capitalizes on nucleosome breathing.Histone glutamine methylation afFACTing rDNA transcription.Histone chaperone Chz1 facilitates the disfavouring property of Spt16 to H2A.Z-containing genes in Saccharomyces cerevisiae.Acetylation-Dependent Recruitment of the FACT Complex and Its Role in Regulating Pol II Occupancy Genome-Wide in Saccharomyces cerevisiae.Histone chaperones FACT and Spt6 prevent histone variants from turning into histone deviants.Structure-specific recognition protein-1 (SSRP1) is an elongated homodimer that binds histones.
P2860
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P2860
Structural and functional analysis of the Spt16p N-terminal domain reveals overlapping roles of yFACT subunits
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structural and functional anal ...... apping roles of yFACT subunits
@ast
Structural and functional anal ...... apping roles of yFACT subunits
@en
Structural and functional anal ...... apping roles of yFACT subunits
@nl
type
label
Structural and functional anal ...... apping roles of yFACT subunits
@ast
Structural and functional anal ...... apping roles of yFACT subunits
@en
Structural and functional anal ...... apping roles of yFACT subunits
@nl
prefLabel
Structural and functional anal ...... apping roles of yFACT subunits
@ast
Structural and functional anal ...... apping roles of yFACT subunits
@en
Structural and functional anal ...... apping roles of yFACT subunits
@nl
P2093
P2860
P3181
P356
P1476
Structural and functional anal ...... apping roles of yFACT subunits
@en
P2093
Andrew P VanDemark
Christopher P Hill
David J Stillman
Laura McCullough
Robert Rawlins
Shayla Bentley
Tim Formosa
P2860
P304
P3181
P356
10.1074/JBC.M708682200
P407
P50
P577
2008-02-22T00:00:00Z