Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90
about
Synthesis of macrolactam analogues of radicicol and their binding to heat shock protein Hsp90Synthesis of benzisoxazoles by the [3 + 2] cycloaddition of in situ generated nitrile oxides and arynes.Solution-phase synthesis of a diverse library of benzisoxazoles utilizing the [3 + 2] cycloaddition of in situ-generated nitrile oxides and arynesAdvances in the discovery and development of heat-shock protein 90 inhibitors for cancer treatment.Synthesis, characterization, and pharmacological evaluation of novel azolo- and azinothiazinones containing 2,4-dihydroxyphenyl substituent as anticancer agents.Synthesis and SAR study of N-(4-hydroxy-3-(2-hydroxynaphthalene-1-yl)phenyl)-arylsulfonamides: heat shock protein 90 (Hsp90) inhibitors with submicromolar activity in an in vitro assay.Discovery and development of heat shock protein 90 inhibitors.Synthesis of 2-(2,4-dihydroxyphenyl)thieno-1,3-thiazin-4-ones, their lipophilicity and anticancer activity in vitro.Applications of Palladium-Catalyzed C-N Cross-Coupling Reactions.Discovery of new heat shock protein 90 inhibitors using virtual co-crystallized pharmacophore generation.DFT STUDY OF THE PROTONATION AND DEPROTONATION ENTHALPIES OF BENZOXAZOLE, 1,2-BENZISOXAZOLE AND 2,1-BENZISOXAZOLE AND IMPLICATIONS FOR THE STRUCTURES AND ENERGIES OF THEIR ADDUCTS WITH EXPLICIT WATER MOLECULESSynthesis of 5,6-dihydro-4H -benzo[d ]isoxazol-7-one and 5,6-dihydro-4H -isoxazolo[5,4-c ]pyridin-7-one Derivatives as Potential Hsp90 Inhibitors
P2860
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P2860
Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90
@ast
Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90
@en
Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90
@nl
type
label
Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90
@ast
Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90
@en
Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90
@nl
prefLabel
Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90
@ast
Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90
@en
Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90
@nl
P2093
P356
P1476
Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90
@en
P2093
Ariamala Gopalsamy
Frank Boschelli
Frederick Lee
Jaison Jacob
Jennifer Golas
John Ellingboe
Kristin Svenson
Mark Johnson
P304
P356
10.1021/JM701385C
P407
P50
P577
2008-01-16T00:00:00Z