Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Vα14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids
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The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentationHow do natural killer T cells help B cells?Recognition of Microbial Glycolipids by Natural Killer T CellsCoevolution of T-cell receptors with MHC and non-MHC ligandsTurned on by danger: activation of CD1d-restricted invariant natural killer T cellsDifferential Recognition of CD1d-α-Galactosyl Ceramide by the Vβ8.2 and Vβ7 Semi-invariant NKT T Cell ReceptorsThe crystal structure of avian CD1 reveals a smaller, more primordial antigen-binding pocket compared to mammalian CD1Structural Evaluation of Potent NKT Cell Agonists: Implications for Design of Novel Stimulatory LigandsMechanisms for Glycolipid Antigen-Driven Cytokine Polarization by V 14i NKT CellsLipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cellsThe diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinityThe Vα14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding modeA Molecular Basis for NKT Cell Recognition of CD1d-Self-AntigenCardiolipin Binds to CD1d and Stimulates CD1d-Restricted T Cells in the Normal Murine RepertoireRecognition of β-linked self glycolipids mediated by natural killer T cell antigen receptorsCutting Edge: Structural Basis for the Recognition of -Linked Glycolipid Antigens by Invariant NKT CellsUnique Interplay between Sugar and Lipid in Determining the Antigenic Potency of Bacterial Antigens for NKT CellsStructural Basis for the Recognition of C20:2-αGalCer by the Invariant Natural Killer T Cell Receptor-like Antibody L363Glycolipids that Elicit IFN-γ-Biased Responses from Natural Killer T CellsStructural and Functional Characterization of a Novel Nonglycosidic Type I NKT Agonist with Immunomodulatory PropertiesInvariant natural killer T cells and their ligands: focus on multiple sclerosisGlobosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cellsDetermination of cellular lipids bound to human CD1d molecules.Innate-like control of human iNKT cell autoreactivity via the hypervariable CDR3beta loop.Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant.Lipid and glycolipid antigens of CD1d-restricted natural killer T cells.Antigen-dependent versus -independent activation of invariant NKT cells during infectionNatural killer T cell recognition of lipid antigens.T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoirePresentation of lipid antigens by CD1 glycoproteins.Identification of self-lipids presented by CD1c and CD1d proteins.Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipidsNatural killer T cells in health and disease.Recognition of CD1d-restricted antigens by natural killer T cells.CD1d presentation of glycolipids.Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands.Identification of iGb3 and iGb4 in melanoma B16F10-Nex2 cells and the iNKT cell-mediated antitumor effect of dendritic cells primed with iGb3Endosomal processing for antigen presentation mediated by CD1 and Class I major histocompatibility complex: roads to display or destruction.The evolved functions of CD1 during infection.γδ T cell receptor ligands and modes of antigen recognition
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P2860
Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Vα14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Crystal Structures of Mouse CD ...... f Foreign and Self Glycolipids
@ast
Crystal Structures of Mouse CD ...... f Foreign and Self Glycolipids
@en
Crystal Structures of Mouse CD ...... f Foreign and Self Glycolipids
@nl
type
label
Crystal Structures of Mouse CD ...... f Foreign and Self Glycolipids
@ast
Crystal Structures of Mouse CD ...... f Foreign and Self Glycolipids
@en
Crystal Structures of Mouse CD ...... f Foreign and Self Glycolipids
@nl
prefLabel
Crystal Structures of Mouse CD ...... f Foreign and Self Glycolipids
@ast
Crystal Structures of Mouse CD ...... f Foreign and Self Glycolipids
@en
Crystal Structures of Mouse CD ...... f Foreign and Self Glycolipids
@nl
P2093
P2860
P921
P1476
Crystal Structures of Mouse CD ...... f Foreign and Self Glycolipids
@en
P2093
Albert Bendelac
Luc Teyton
Paul B Savage
P2860
P304
P356
10.1016/J.JMB.2008.01.061
P407
P577
2008-04-04T00:00:00Z