Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors

Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors

Item
http://www.wikidata.org/entity/Q27650292
Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitorsAnomalous dispersion analysis of inhibitor flexibility: a case study of the kinase inhibitor H-89Creating novel activated factor XI inhibitors through fragment based lead generation and structure aided drug designTarget immobilization as a strategy for NMR-based fragment screening: comparison of TINS, STD, and SPR for fragment hit identification.Integrating surface plasmon resonance biosensor-based interaction kinetic analyses into the lead discovery and optimization process.Biosensor-based small molecule fragment screening with biolayer interferometry.The benefits of constructing leads from fragment hits.Emerging role of surface plasmon resonance in fragment-based drug discovery.A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline.Structure-activity relationships in the development of allosteric hepatitis C virus RNA-dependent RNA polymerase inhibitors: ten years of research.A study of the allosteric inhibition of HCV RNA-dependent RNA polymerase and implementing virtual screening for the selection of promising dual-site inhibitors with low resistance potential.Combination of pharmacophore hypothesis and molecular docking to identify novel inhibitors of HCV NS5B polymerase.
P2860

Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors

Item
http://www.wikidata.org/entity/Q27650292
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors
@ast
Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors
@en
Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors
@nl
type
label
Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors
@ast
Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors
@en
Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors
@nl
prefLabel
Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors
@ast
Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors
@en
Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors
@en
P2093
P304
P31
P356
10.1016/J.BMCL.2008.03.056
P407
P433
P478
P50
P577
P698