Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin B
about
Crystal structure of the parasite inhibitor chagasin in complex with papain allows identification of structural requirements for broad reactivity and specificity determinants for target proteasesCrystal structure of human cystatin C stabilized against amyloid formationStefin A displaces the occluding loop of cathepsin B only by as much as required to bind to the active site cleftExoerythrocytic Plasmodium parasites secrete a cysteine protease inhibitor involved in sporozoite invasion and capable of blocking cell death of host hepatocytesSolution structure of a phytocystatin from Ananas comosus and its molecular interaction with papainComputational analysis of the cathepsin B inhibitors activities through LR-MMPBSA binding affinity calculation based on docked complex.QSAR models for predicting cathepsin B inhibition by small molecules--continuous and binary QSAR models to classify cathepsin B inhibition activities of small molecules.Multi-conformation 3D QSAR study of benzenesulfonyl-pyrazol-ester compounds and their analogs as cathepsin B inhibitors.Prokaryote-derived protein inhibitors of peptidases: A sketchy occurrence and mostly unknown functionThe macromolecular complex of ICP and falcipain-2 from Plasmodium: preparation, crystallization and preliminary X-ray diffraction analysis.The lysosome among targets of metformin: new anti-inflammatory uses for an old drug?Evaluation of variability in high-resolution protein structures by global distance scoring.
P2860
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P2860
Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin B
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Displacement of the occluding ...... nhibition of human cathepsin B
@ast
Displacement of the occluding ...... nhibition of human cathepsin B
@en
Displacement of the occluding ...... nhibition of human cathepsin B
@nl
type
label
Displacement of the occluding ...... nhibition of human cathepsin B
@ast
Displacement of the occluding ...... nhibition of human cathepsin B
@en
Displacement of the occluding ...... nhibition of human cathepsin B
@nl
prefLabel
Displacement of the occluding ...... nhibition of human cathepsin B
@ast
Displacement of the occluding ...... nhibition of human cathepsin B
@en
Displacement of the occluding ...... nhibition of human cathepsin B
@nl
P2093
P2860
P356
P1476
Displacement of the occluding ...... nhibition of human cathepsin B
@en
P2093
Anna Ljunggren
Izabela Redzynia
Joanne C Krupa
John S Mort
Magnus Abrahamson
P2860
P304
P356
10.1074/JBC.M802064200
P407
P577
2008-08-15T00:00:00Z