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Structural basis for translation termination on the 70S ribosome

Structural basis for translation termination on the 70S ribosome

http://www.wikidata.org/entity/Q27651016

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Structural basis for the dsRNA specificity of the Lassa virus NP exonuclease Structure based hypothesis of a mitochondrial ribosome rescue mechanism A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome Bioinformatic, structural, and functional analyses support release factor-like MTRF1 as a protein able to decode nonstandard stop codons beginning with adenine in vertebrate mitochondria Evolution of protein synthesis from an RNA world Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu Fine-tuning of the ribosomal decoding center by conserved methyl-modifications in the Escherichia coli 16S rRNA Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome.Ribosome-based quality control of mRNA and nascent peptides Structural insights into ribosome translocation Crystal structures of 70S ribosomes bound to release factors RF1, RF2 and RF3 Therapeutic suppression of premature termination codons: mechanisms and clinical considerations (review)Termination of protein synthesis in mammalian mitochondria The Structural Basis for mRNA Recognition and Cleavage by the Ribosome-Dependent Endonuclease RelE Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl group of A76 of the unacylated A-site tRNA Insights into Translational Termination from the Structure of RF2 Bound to the Ribosome Crystal structure of a translation termination complex formed with release factor RF2 Structural insights into eRF3 and stop codon recognition by eRF1 Structures of the ribosome in intermediate states of ratcheting The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome Structural aspects of messenger RNA reading frame maintenance by the ribosome Structure of the 70S ribosome bound to release factor 2 and a substrate analog provides insights into catalysis of peptide release Recognition of the amber UAG stop codon by release factor RF1 Omnipotent role of archaeal elongation factor 1 alpha (EF1 ) in translational elongation and termination, and quality control of protein synthesis Crystal structure of the eukaryotic ribosome Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome Structural basis for translation termination by archaeal RF1 and GTP-bound EF1 complex Allosteric control of the ribosome by small-molecule antibiotics.Crystal structure of the hybrid state of ribosome in complex with the guanosine triphosphatase release factor 3 Crystal structure of release factor RF3 trapped in the GTP state on a rotated conformation of the ribosome Selectivity of stop codon recognition in translation termination is modulated by multiple conformations of GTS loop in eRF1 Structural Basis for the Rescue of Stalled Ribosomes: Structure of YaeJ Bound to the Ribosome Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor Crystal Structure of the 70S Ribosome Bound with the Q253P Mutant Form of Release Factor RF2 Structure and dynamics in solution of the stop codon decoding N-terminal domain of the human polypeptide chain release factor eRF1 Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome YoeB-ribosome structure: a canonical RNase that requires the ribosome for its specific activity RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA Identification of residues required for stalled-ribosome rescue in the codon-independent release factor YaeJ Structure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNP

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P2860

Structural basis for translation termination on the 70S ribosome

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2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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Structural basis for translation termination on the 70S ribosome

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Structural basis for translation termination on the 70S ribosome

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Structural basis for translation termination on the 70S ribosome

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Structural basis for translation termination on the 70S ribosome

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Structural basis for translation termination on the 70S ribosome

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Structural basis for translation termination on the 70S ribosome

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Martin Laurberg

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Characterization of three proteins involved in polypeptide chain termination.

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