The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore †
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Structure-Based Design, Synthesis, and Evaluation of 2′-(2-Hydroxyethyl)-2′-deoxyadenosine and the 5′-Diphosphate Derivative as Ribonucleotide Reductase InhibitorsEvaluating the Therapeutic Potential of a Non-Natural Nucleotide That Inhibits Human Ribonucleotide ReductaseRole of Arginine 293 and Glutamine 288 in Communication between Catalytic and Allosteric Sites in Yeast Ribonucleotide ReductaseMolecular Strategies of Deoxynucleotide Triphosphate Supply Inhibition Used in the Treatment of Gynecologic MalignanciesDetermination of triapine, a ribonucleotide reductase inhibitor, in human plasma by liquid chromatography tandem mass spectrometry.Targeting the Large Subunit of Human Ribonucleotide Reductase for Cancer Chemotherapy.A compendium of cyclic sugar amino acids and their carbocyclic and heterocyclic nitrogen analogues.Unique molecular mechanisms for maintenance and alteration of genetic information in the budding yeast Saccharomyces cerevisiae.Structure-Guided Synthesis and Mechanistic Studies Reveal Sweetspots on Naphthyl Salicyl Hydrazone Scaffold as Non-Nucleosidic Competitive, Reversible Inhibitors of Human Ribonucleotide Reductase.
P2860
Q27657014-B633EC96-163B-4DDB-BACA-05467186AD53Q27671797-675D0113-A63E-4587-89A8-01E6FACAA1E9Q27678275-882C947D-E1B4-421D-A891-15611A12EB48Q34482362-A5B65AC2-CFD5-4734-A389-7F7D79A00117Q35560319-C6E82FA0-0828-4B06-817D-C62D3A4B4B88Q36353167-A6C047D5-DE73-4736-9812-98FBB78DFFDDQ38129764-D3686C09-54AA-440A-8B15-86CEFDCA03F4Q46246407-1ACD0DDB-3688-4325-ADFD-67B77043D839Q48099410-2C088BB1-AA63-43DA-AB86-7F0405A302DE
P2860
The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore †
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The Structural Basis for Pepti ...... nally Flexible Pharmacophore †
@ast
The Structural Basis for Pepti ...... nally Flexible Pharmacophore †
@en
The Structural Basis for Pepti ...... nally Flexible Pharmacophore †
@nl
type
label
The Structural Basis for Pepti ...... nally Flexible Pharmacophore †
@ast
The Structural Basis for Pepti ...... nally Flexible Pharmacophore †
@en
The Structural Basis for Pepti ...... nally Flexible Pharmacophore †
@nl
prefLabel
The Structural Basis for Pepti ...... nally Flexible Pharmacophore †
@ast
The Structural Basis for Pepti ...... nally Flexible Pharmacophore †
@en
The Structural Basis for Pepti ...... nally Flexible Pharmacophore †
@nl
P2093
P2860
P356
P1476
The Structural Basis for Pepti ...... nally Flexible Pharmacophore †
@en
P2093
Barry S Cooperman
Chris Dealwis
Elizabeth Helmbrecht
James W Fairman
John LaMacchia
Nathan R Kreischer
Sanath R Wijerathna
P2860
P304
P356
10.1021/JM800350U
P407
P577
2008-08-14T00:00:00Z